Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | BHMT | Q93088 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2133661 | 0.86 | EPHX1 (0.42) | ALDH1A1HSD17B10RNPEPEPHX1BHMT | |
| SCHEMBL2134884 | 0.84 | EPHX1 (0.44) | ALDH1A1HSD17B10EPHX1BHMTMAPT | |
| SCHEMBL2138208 | 0.84 | EPHX1 (0.44) | ALDH1A1HSD17B10EPHX1BHMTMAPT | |
| SCHEMBL2135022 | 0.79 | EPHX1 (0.39) | ALDH1A1HSD17B10RNPEPEPHX1BHMT | |
| SCHEMBL2136786 | 0.79 | RNPEP (0.31) | RNPEPBHMTBHMT2MAPTGABRR1 | |
| SCHEMBL2134774 | 0.78 | SMN1; SMN2 (0.38) | ALDH1A1EPHX1KDM4E | |
| SCHEMBL2137810 | 0.78 | EPHX1 (0.42) | ALDH1A1HSD17B10RNPEPEPHX1BHMT | |
| SCHEMBL2132216 | 0.76 | RNPEP (0.36) | ALDH1A1RNPEPLMNA | |
| SCHEMBL2139050 | 0.76 | TSHR (0.32) | EPHX1 | |
| SCHEMBL2133549 | 0.76 | EPHX1 (0.44) | ALDH1A1HSD17B10EPHX1BHMTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120101294-A1 | PROCESS FOR PRODUCING (FLUOROALKYLTHIO) ACETIC ACID ESTER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101294-A1 | PROCESS FOR PRODUCING (FLUOROALKYLTHIO) ACETIC ACID ESTER | GRHPR, AKR7A2, FAR1 | ALDH1A1 41/4885HSD17B10 232/4885RNPEP 1177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.