SCHEMBL21342825

SCHEMBL21342825

Clc1ccc2c(c1)C1(c3ccccc3Oc3ccc(Br)cc31)c1ccccc1-2

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
AHR P35869 5/20 0.41
PDK2 Q15119 5/20 0.40
MAPK1 P28482 1/20 0.38
AKR1A1 P14550 1/20 0.36
AKR1B1 P15121 1/20 0.36
OPRM1 P35372 1/20 0.34
OPRD1 P41143 1/20 0.34
DRD2 P14416 2/20 0.32
DRD4 P21917 2/20 0.32
HRH4 Q9H3N8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21517441 1.00 AHR (0.41) AHRPDK2MAPK1AKR1A1AKR1B1
SCHEMBL21517552 0.95 AHR (0.42) AHRPDK2MAPK1AKR1A1AKR1B1
SCHEMBL21517359 0.95 AHR (0.42) AHRPDK2MAPK1AKR1A1AKR1B1
SCHEMBL24027778 0.92 PDK2 (0.40) AHRPDK2MAPK1AKR1A1AKR1B1
SCHEMBL29869118 0.92 PDK2 (0.43) AHRPDK2MAPK1OPRM1OPRD1
SCHEMBL30913036 0.91 AHR (0.42) AHRPDK2MAPK1AKR1A1AKR1B1
SCHEMBL15713385 0.89 AHR (0.52) AHRPDK2OPRM1OPRD1DRD2
SCHEMBL23285069 0.89 PDK2 (0.47) AHRPDK2MAPK1AKR1A1AKR1B1
SCHEMBL22891353 0.89 MAPK1 (0.45) AHRPDK2MAPK1AKR1A1AKR1B1
SCHEMBL31753805 0.89 MAPK1 (0.45) AHRPDK2MAPK1AKR1A1AKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019172699-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2019-09-12 WO disclosed