Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 5/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.35 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21517552 | 0.93 | AHR (0.42) | AHRPDK2MAPK1AKR1A1AKR1B1 | |
| SCHEMBL21342825 | 0.91 | AHR (0.41) | AHRPDK2MAPK1AKR1A1AKR1B1 | |
| SCHEMBL21517441 | 0.91 | AHR (0.41) | AHRPDK2MAPK1AKR1A1AKR1B1 | |
| SCHEMBL29869118 | 0.91 | PDK2 (0.43) | AHRPDK2MAPK1MEN1MAPT | |
| SCHEMBL24027778 | 0.88 | PDK2 (0.40) | AHRPDK2MAPK1FTOMEN1 | |
| SCHEMBL30913037 | 0.87 | AHR (0.52) | AHRPDK2FTOMEN1MAPT | |
| SCHEMBL21305014 | 0.87 | AHR (0.52) | AHRPDK2FTOMEN1MAPT | |
| SCHEMBL22891353 | 0.87 | MAPK1 (0.45) | AHRPDK2MAPK1MEN1MAPT | |
| SCHEMBL31753805 | 0.87 | MAPK1 (0.45) | AHRPDK2MAPK1MEN1MAPT | |
| SCHEMBL29651964 | 0.87 | AHR (0.50) | AHRPDK2FTOMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084852-A | Spiro [ 9H-fluorene-9, 9' - [9H ] xanthene ] organic photoelectric material, and preparation method and application thereof | 河南省科学院化学研究所有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-118084852-A | Spiro [ 9H-fluorene-9, 9' - [9H ] xanthene ] organic photoelectric material, and preparation method and application thereof | 河南省科学院化学研究所有限公司 | 2024-05-28 | — | — | CN | disclosed |