SCHEMBL21342833

SCHEMBL21342833

Clc1ccc2c(c1)C1(c3ccccc3Sc3ccccc31)c1cccc(Br)c1-2

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 4/20 0.40
ACHE P22303 2/20 0.37
BCHE P06276 1/20 0.37
NOX1 Q9Y5S8 1/20 0.37
HPGD P15428 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
NPSR1 Q6W5P4 1/20 0.34
PTGES O14684 1/20 0.33
ALDH1A1 P00352 1/20 0.32
AKR1A1 P14550 1/20 0.32
AKR1B1 P15121 1/20 0.32
MLNR O43193 1/20 0.32
NR1I2 O75469 1/20 0.32
ESR1 P03372 1/20 0.32
CHRM2 P08172 1/20 0.32
CHRM4 P08173 1/20 0.32
HTR1A P08908 1/20 0.32
ADRA2A P08913 1/20 0.32
ADORA3 P0DMS8 1/20 0.32
CHRM1 P11229 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24027917 0.90 PDK2 (0.39) PDK2ACHEBCHENOX1HPGD
SCHEMBL19001688 0.86 PDK2 (0.47) PDK2PTGESALDH1A1AKR1A1AKR1B1
SCHEMBL23697040 0.84 PDK2 (0.47) PDK2ACHEBCHENOX1L3MBTL1
SCHEMBL21517232 0.82 PDK2 (0.40) PDK2ACHEBCHENOX1HPGD
SCHEMBL19728551 0.82 PDK2 (0.43) PDK2PTGESALDH1A1AKR1A1AKR1B1
SCHEMBL22891491 0.81 PDK2 (0.47) PDK2ACHEBCHENOX1HPGD
SCHEMBL20687337 0.80 PDK2 (0.43) PDK2AKR1A1AKR1B1CYP1A2
SCHEMBL19001693 0.80 PDK2 (0.42) PDK2PTGESALDH1A1AKR1A1AKR1B1
SCHEMBL20687343 0.80 PDK2 (0.38) PDK2PTGESAKR1A1AKR1B1
SCHEMBL20687341 0.80 PDK2 (0.41) PDK2PTGESAKR1A1AKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019172699-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2019-09-12 WO disclosed