Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.38 |
| ▸ | MEN1 | O00255 | 9/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 5/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 2/20 | 0.33 |
| ▸ | NR0B1 | P51843 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21342158 | 0.98 | MAPT (0.38) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL21342157 | 0.90 | AKR1B1 (0.34) | MAPTMEN1KMT2AKDM4EPOLB | |
| SCHEMBL21342890 | 0.90 | KMT2A (0.45) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL21342502 | 0.85 | POLB (0.32) | MAPTMEN1KMT2AKDM4EPOLB | |
| SCHEMBL21342169 | 0.85 | DTYMK (0.30) | KDM4E | |
| SCHEMBL21342160 | 0.84 | POLB (0.32) | MAPTMEN1KMT2AKDM4EPOLB | |
| SCHEMBL21342159 | 0.82 | KDM4E (0.31) | MEN1KMT2AKDM4E | |
| SCHEMBL21342165 | 0.82 | KMT2A (0.40) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL21342486 | 0.82 | KMT2A (0.40) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL21342487 | 0.81 | KMT2A (0.38) | MAPTMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210094922-A1 | Dyes for Analysis of Soluble Protein Aggregates or Misfolded Protein Oligomers | PENN STATE RES FOUND (US) | 2021-04-01 | — | — | US | disclosed |
| WO-2019173607-A1 | DYES FOR ANALYSIS OF SOLUBLE PROTEIN AGGREGATES OR MISFOLDED PROTEIN OLIGOMERS | THE PENN STATE RESEARCH FOUNDATION (US) | 2019-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210094922-A1 | Dyes for Analysis of Soluble Protein Aggregates or Misfolded Protein Oligomers | HSPBP1, HTT, HSPA5 | MAPT 4/4885MEN1 4014/4885KMT2A 4328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.