Sugi Predict

Sugi Predict / Targets / HSPBP1

HSPBP1

Hsp70-binding protein 1 · Q9NZL4 · HSPBP1 on Sugi Atlas →

0 patent compounds predicted against HSPBP1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to HSPBP1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
OGX-427 in Castration Resistant Prostate Cancer Patients PHASE2COMPLETED
Gemcitabine, Docetaxel, and Hydroxychloroquine in Treating Participants With Recurrent or Refractory Osteosarcoma PHASE1/PHASE2ACTIVE_NOT_RECRUITING
Targeting the Tumor Microenvironment in R/M SCCHN PHASE1/PHASE2UNKNOWN
Targeting Endoplasmic Reticulum Stress in Human Hypertension PHASE1/PHASE2RECRUITING
Colchicine for Amyotrophic Lateral Sclerosis PHASE2COMPLETED
Belimumab Treatment of Emphysema Patients With Anti-GRP78 Autoantibodies PHASE2COMPLETED
Study of Oral CNF2024 (BIIB021) in Advanced Solid Tumors PHASE1COMPLETED
Safety and Pharmacology of SNX-5422 Plus Carboplatin and Paclitaxel in Subjects With Solid Tumors PHASE1COMPLETED
HS-201, an HSP90 Inhibitor-linked Verteporfin for Detection of Solid Malignancies PHASE1WITHDRAWN
Once or Twice Daily Administration of BIIB021 to Subjects With Advanced Solid Tumors PHASE1COMPLETED
SNX-5422 to Treat Solid Tumor Cancers and Lymphomas PHASE1COMPLETED
Exercise on Expression of Heat Shock Protein 70 in Arterial Risk nanCOMPLETED
LncRNA Nicotinamide Nucleotide Transhydrogenase-Antisense RNA1 NNT-AS1 in CRC nanCOMPLETED
Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq) nanRECRUITING
Reduced Ventilator-Free Days and Bacterial Colonization of Sub-Glottic Secretions nanWITHDRAWN
Acute Passive Heating in Healthy Older Adults nanCOMPLETED
Trial of Nonsurgical Treatment of Intermittent Claudication Due to Femoro-popliteal Disease nanCOMPLETED
BASE HSP110 : A New Therapeutic Target and a New Marker for Prognosis of Type MSI Colorectal Cancer nanUNKNOWN
Perfusion-Induced Hyperthermia for Metastatic Carcinoma nanCOMPLETED
Muscle Wasting in Cancer (MWIC) nanCOMPLETED
Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia nanRECRUITING
Role of Sorcin and Annexin A3 in Breast Cancer Patients nanUNKNOWN
Possible Diagnostic Protein Markers in Schistosoma Related Bladder Diseases. nanNOT_YET_RECRUITING
Cardioprotective Benefit of Passive Heat Therapy in Higher-Level Spinal Cord Injury: Safety and Proof of Concept nanUNKNOWN
The Role of HSP90 in Peripheral Vascular Lesions of Diabetic Atherosclerosis nanCOMPLETED
Heat Shock Protein (HSP) 70 to Quantify and Characterize Circulating Tumor Cells nanUNKNOWN
Chronic Passive Heating in Healthy Older Adults nanCOMPLETED
Establishment of Human Cellular Disease Models for Wilson Disease nanCOMPLETED
Chronic Heat Therapy for Improving Vascular Health nanCOMPLETED
Local Heat-Stress as a Mechanism of Hearing Preservation nanWITHDRAWN

Related proteins — ESM-2 sequence neighbours (a HSPBP1 binder may also engage these)

ProteinNameSimilarity
Q4R588 — 1.000 Q4R588 →
Q99P31 — 1.000 Q99P31 →
Q6IMX7 — 1.000 Q6IMX7 →
Q8BQX5 — 0.970 Q8BQX5 →
Q96DC7 — 0.970 Q96DC7 →
Q5NVK5 — 0.969 Q5NVK5 →
Q5EA80 — 0.969 Q5EA80 →
Q3B7U9 — 0.969 Q3B7U9 →
A5A779 — 0.969 A5A779 →
M0RDU0 — 0.968 M0RDU0 →
P23610 — 0.967 P23610 →
Q86Y56 — 0.967 Q86Y56 →
PKN1 Serine/threonine-protein kinase N1 0.966 landscape →
O35465 — 0.966 O35465 →
Q9JHK4 — 0.966 Q9JHK4 →
Q9HA65 — 0.966 Q9HA65 →
Q9ESJ4 — 0.965 Q9ESJ4 →
Q9BV38 — 0.965 Q9BV38 →
P70268 — 0.965 P70268 →
Q9BSK4 — 0.965 Q9BSK4 →
Q6ZT62 — 0.965 Q6ZT62 →
A6NLP5 — 0.965 A6NLP5 →
F1MX48 — 0.964 F1MX48 →
A1A4I4 — 0.964 A1A4I4 →
INF2 Inverted formin-2 0.964 landscape →
C5IJB0 — 0.964 C5IJB0 →
Q3SZD4 — 0.964 Q3SZD4 →
SARM1 NAD(+) hydrolase SARM1 0.963 landscape →
Q9Z2Y1 — 0.963 Q9Z2Y1 →
Q9Z2G1 — 0.963 Q9Z2G1 →