Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 14/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14533954 | 0.88 | GRM5 (0.76) | GRM5KCNH2CLK4METAP2METAP1 | |
| SCHEMBL9958239 | 0.82 | KDM4E (0.54) | GRM5METAP1 | |
| SCHEMBL31252166 | 0.82 | KDM4E (0.54) | GRM5METAP1 | |
| SCHEMBL9958124 | 0.82 | KDM4E (0.54) | GRM5METAP1 | |
| SCHEMBL4191006 | 0.82 | GRM5 (0.85) | GRM5KCNH2 | |
| SCHEMBL6625981 | 0.81 | GRM5 (0.48) | GRM5KCNH2 | |
| SCHEMBL3270281 | 0.81 | GRM5 (0.72) | GRM5KCNH2 | |
| SCHEMBL5108108 | 0.79 | GRM5 (0.72) | GRM5 | |
| SCHEMBL1133442 | 0.78 | CLK4 (0.66) | GRM5CLK4 | |
| SCHEMBL29472032 | 0.78 | CLK4 (0.66) | GRM5CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11800789-B2 | Organometallic compound, organic light-emitting device including the same, and diagnostic composition including the organometallic compound | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2023-10-24 | — | — | US | disclosed |
| WO-2023061263-A1 | SHP2 INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 北京泰德制药股份有限公司 | 2023-04-20 | — | — | WO | disclosed |
| WO-2019172699-A1 | COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME | 주식회사 엘지화학 | 2019-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11800789-B2 | Organometallic compound, organic light-emitting device including the same, and diagnostic composition including the organometallic compound | LEF1, ORC3, OCIAD1 | GRM5 2041/4885KCNH2 2447/4885CLK4 3864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.