Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | CASP2 | P42575 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19934140 | 0.94 | MEN1 (0.64) | MEN1KMT2ATSHREPHX2RECQL | |
| SCHEMBL2771342 | 0.88 | RECQL (0.63) | MEN1KMT2ATSHREPHX2LMNA | |
| SCHEMBL13376980 | 0.86 | RECQL (0.61) | TSHREPHX2LMNARECQLCASP2 | |
| SCHEMBL1709284 | 0.85 | MEN1 (0.56) | MEN1KMT2ATSHREPHX2RECQL | |
| SCHEMBL16864016 | 0.85 | CASP2 (0.69) | TSHREPHX2RECQLCASP2 | |
| SCHEMBL15399777 | 0.83 | TSHR (0.65) | MEN1KMT2ATSHREPHX2LMNA | |
| SCHEMBL23052003 | 0.83 | CASP2 (0.67) | EPHX2RECQLCASP2CA12CA2 | |
| SCHEMBL6584132 | 0.83 | CASP2 (0.67) | EPHX2RECQLCASP2CA12CA2 | |
| SCHEMBL8576702 | 0.83 | CASP2 (0.67) | EPHX2RECQLCASP2CA12CA2 | |
| SCHEMBL9118774 | 0.83 | CASP2 (0.67) | EPHX2RECQLCASP2CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022087317-A1 | THIOHYDROXYPYRIDINE CHELATES | LUMIPHORE, INC. (US) | 2022-04-28 | — | — | WO | disclosed |
| WO-2019173639-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | LUMIPHORE, INC. (US) | 2019-09-12 | — | — | WO | disclosed |