Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.71 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.46 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.35 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.35 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11727234 | 1.00 | USP2 (0.71) | USP2HTTLPAR5PLA2G2CLMNA | |
| SCHEMBL10412965 | 0.92 | USP2 (0.67) | USP2HTTLPAR5PLA2G2CLMNA | |
| SCHEMBL12267478 | 0.90 | USP2 (0.58) | USP2HTTLPAR5PLA2G2CLMNA | |
| SCHEMBL29837928 | 0.89 | USP2 (0.79) | USP2HTTLPAR5PLA2G2CLMNA | |
| SCHEMBL8622815 | 0.89 | USP2 (0.79) | USP2HTTLPAR5PLA2G2CLMNA | |
| SCHEMBL8620507 | 0.89 | USP2 (0.79) | USP2HTTLPAR5PLA2G2CLMNA | |
| SCHEMBL8619644 | 0.89 | USP2 (0.79) | USP2HTTLPAR5PLA2G2CLMNA | |
| SCHEMBL8622282 | 0.89 | USP2 (0.79) | USP2HTTLPAR5PLA2G2CLMNA | |
| SCHEMBL6230528 | 0.89 | USP2 (0.79) | USP2HTTLPAR5PLA2G2CLMNA | |
| SCHEMBL11042040 | 0.87 | USP2 (0.75) | USP2HTTLPAR5PLA2G2CLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019172286-A1 | THERAPEUTIC AGENT FOR GLYCOGEN STORAGE DISEASE TYPE IA | 第一三共株式会社 | 2019-09-12 | — | — | WO | disclosed |