Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.44 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | LPAR6 | P43657 | 2/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.33 |
| ▸ | LPAR4 | Q99677 | 2/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21344050 | 0.92 | USP2 (0.71) | USP2HTTLPAR5PLA2G2CMEN1 | |
| SCHEMBL11727234 | 0.92 | USP2 (0.71) | USP2HTTLPAR5PLA2G2CMEN1 | |
| SCHEMBL2931768 | 0.92 | USP2 (0.53) | USP2HTTLPAR5MEN1KMT2A | |
| SCHEMBL18805113 | 0.92 | USP2 (0.53) | USP2HTTLPAR5MEN1KMT2A | |
| SCHEMBL12883079 | 0.92 | USP2 (0.53) | USP2HTTLPAR5MEN1KMT2A | |
| SCHEMBL10044032 | 0.92 | USP2 (0.53) | USP2HTTLPAR5MEN1KMT2A | |
| SCHEMBL15214942 | 0.92 | USP2 (0.53) | USP2HTTLPAR5MEN1KMT2A | |
| SCHEMBL11046670 | 0.92 | USP2 (0.53) | USP2HTTLPAR5MEN1KMT2A | |
| SCHEMBL12267478 | 0.90 | USP2 (0.58) | USP2HTTLPAR5PLA2G2CMEN1 | |
| SCHEMBL7932635 | 0.90 | USP2 (0.55) | USP2HTTLPAR5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4939127-A | SIDE EFFECT REDUCTION | AMERICAN CYANAMID COMPANY (US) | 1990-07-03 | — | — | US | disclosed |
| US-4703130-A | Antihypertensive phosphate derivatives | AMERICAN CYANAMID COMPANY (US) | 1987-10-27 | — | — | US | disclosed |