Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22992246 | 0.94 | ALDH1A1 (0.35) | USP2ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL21344847 | 0.93 | NAMPT (0.35) | USP2ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL21343736 | 0.89 | USP2 (0.34) | USP2ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL22992082 | 0.88 | USP2 (0.36) | USP2ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL21344671 | 0.88 | ALDH1A1 (0.42) | USP2ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL21332069 | 0.87 | CYP2D6 (0.32) | USP2ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL21285240 | 0.87 | PSEN1 (0.32) | USP2ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL22992187 | 0.86 | CGAS (0.32) | ALDH1A1CYP1A2CYP3A4MAPK1 | |
| SCHEMBL22992188 | 0.86 | ALDH1A1 (0.33) | ALDH1A1CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL21343725 | 0.86 | ALDH1A1 (0.35) | ALDH1A1CYP1A2MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019170745-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-09-12 | — | — | WO | disclosed |