Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | SETD7 | Q8WTS6 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19698538 | 1.00 | KDM4E (0.43) | KDM4EPKMGPR119USP30MEN1 | |
| SCHEMBL24982513 | 0.81 | KDM4E (0.41) | KDM4EPKMGPR119USP30MEN1 | |
| SCHEMBL8695092 | 0.81 | KDM4E (0.52) | KDM4EPKMGPR119USP30MEN1 | |
| SCHEMBL24896686 | 0.79 | HSD17B10 (0.58) | USP30MEN1KMT2AHSD17B10 | |
| SCHEMBL26427719 | 0.79 | KDM4E (0.38) | KDM4EPKMGPR119USP30MEN1 | |
| SCHEMBL25717306 | 0.78 | KDM4E (0.50) | KDM4EPKMGPR119USP30MEN1 | |
| SCHEMBL25628792 | 0.77 | KDM4E (0.52) | KDM4EPKMGPR119USP30MEN1 | |
| SCHEMBL24718695 | 0.77 | USP30 (0.47) | KDM4EPKMGPR119USP30MEN1 | |
| SCHEMBL26427290 | 0.76 | KDM4E (0.46) | KDM4EPKMGPR119USP30MEN1 | |
| SCHEMBL27624527 | 0.76 | ACHE (0.58) | KDM4EMEN1KMT2ACHRNB2CHRNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190276414-A1 | CHIRAL RESOLUTION OF AN INTERMEDIATE OF SUVOREXANT AND COCRYSTALS THEREOF | ENANTIA, S.L. (ES) | 2019-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190276414-A1 | CHIRAL RESOLUTION OF AN INTERMEDIATE OF SUVOREXANT AND COCRYSTALS THEREOF | HCRTR1, HCRTR2, GLP1R | KDM4E 147/4885PKM 4232/4885GPR119 151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.