SCHEMBL2134685

SCHEMBL2134685

C[SiH](C)[Zr](C)(C)c1c(C2=CC(C(C)(C)C)=CC2)ccc2c1Cc1ccccc1-2

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.32
PGR P06401 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28119166 0.78 PNMT (0.36) PNMTPGR
SCHEMBL9280866 0.78 PNMT (0.33) PNMT
Hydrochloric Acid SCHEMBL3693755 0.78 PNMT (0.33) PNMT
Fluoride Ion SCHEMBL3470296 0.77 PNMT (0.32) PNMT
SCHEMBL3806739 0.77 PNMT (0.32) PNMT
Hydrochloric Acid SCHEMBL2135868 0.77 PNMT (0.32) PNMT
Hydrochloric Acid SCHEMBL8676755 0.77 PNMT (0.35) PNMTPGR
Hydrochloric Acid SCHEMBL9066343 0.75 PNMT (0.32) PNMT
SCHEMBL6211217 0.74 PNMT (0.33) PNMT
Hydrochloric Acid SCHEMBL8529709 0.73 NPC1 (0.34) PNMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8524627-B2 Activating supports with controlled distribution of OH groups TOTAL RESEARCH & TECHNOLOGY FELUY (BE) 2013-09-03 US disclosed
EP-2328939-B1 ACTIVATING SUPPORTS BASED ON PERFLUORINATED BORONIC ACIDS TOTAL RES & TECHNOLOGY FELUY (BE) 2012-12-12 EP disclosed
US-20120101239-A1 ACTIVATING SUPPORTS WITH CONTROLLED DISTRIBUTION OF OH GROUPS CENTRE NATIONAL DE LA RESCHERCHE SCIENTIFIQUE (FR) 2012-04-26 US disclosed
EP-2251362-A1 Activating supports with controlled distribution of OH groups TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2010-11-17 EP disclosed
US-7759271-B2 Activating supports for metallocene catalysis TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2010-07-20 US disclosed
EP-2172493-A1 Activating supports based on perfluorinated boronic acids TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2010-04-07 EP disclosed
US-20090042720-A1 Activating supports for metallocene catalysis TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2009-02-12 US disclosed
EP-1559730-A1 Activating supports for metallocene catalysis TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2005-08-03 EP disclosed