SCHEMBL21347710

SCHEMBL21347710

CC(=O)c1ccccc1C(=O)NCCN1CCCCC1

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.55
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
NPSR1 Q6W5P4 1/20 0.55
CYP1A2 P05177 1/20 0.55
CYP2D6 P10635 1/20 0.55
CYP2C9 P11712 1/20 0.55
KDM4E B2RXH2 1/20 0.53
HSD17B10 Q99714 1/20 0.53
ALDH1A1 P00352 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24333908 0.99 NPSR1 (0.56) POLBMEN1KMT2ANPSR1CYP1A2
SCHEMBL17199590 0.86 KDM4E (0.58) POLBMEN1KMT2AKDM4EHSD17B10
SCHEMBL21347706 0.86 KMT2A (0.66) MEN1KMT2ACYP1A2CYP2D6ALDH1A1
SCHEMBL26506323 0.86 MEN1 (0.53) POLBMEN1KMT2ANPSR1CYP1A2
SCHEMBL13164063 0.86 NPSR1 (0.58) POLBMEN1KMT2ANPSR1CYP1A2
SCHEMBL11484492 0.85 MEN1 (0.57) POLBMEN1KMT2ANPSR1CYP1A2
SCHEMBL21883951 0.85 MEN1 (0.52) POLBMEN1KMT2ANPSR1CYP1A2
SCHEMBL13164061 0.84 NPSR1 (0.59) POLBMEN1KMT2ANPSR1ALDH1A1
SCHEMBL2964718 0.84 IKBKB (0.57) POLBMEN1KMT2ANPSR1CYP1A2
SCHEMBL20879965 0.84 MEN1 (0.54) POLBMEN1KMT2ANPSR1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230381323-A1 RELEASABLE CONJUGATES FISH & RICHARDSON PC 2023-11-30 US disclosed
US-11786599-B2 Releasable conjugates QUIAPEG PHARMACEUTICALS AB (SE) 2023-10-17 US disclosed
EP-4011396-A1 RELEASABLE CONJUGATES QuiaPEG Pharmaceuticals AB (SE) 2022-06-15 EP disclosed
US-11357828-B2 Releasable GLP-1 conjugates QUIAPEG PHARMACEUTICALS AB (SE) 2022-06-14 US disclosed
EP-3592393-B1 RELEASABLE CONJUGATES QUIAPEG PHARMACEUTICALS AB (SE) 2021-12-01 EP disclosed
WO-2020053815-A1 RELEASABLE GLP-1 CONJUGATES QUIAPEG PHARMACEUTICALS AB (SE) 2020-03-19 WO disclosed
WO-2019171358-A1 RELEASABLE ANTIBODY CONJUGATES QUIAPEG PHARMACEUTICALS AB (SE) 2019-09-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230381323-A1 RELEASABLE CONJUGATES GUSB, ABCB11, UGT2B7 POLB 1863/4885MEN1 2694/4885KMT2A 4144/4885
US-11357828-B2 Releasable GLP-1 conjugates GLP1R, GIPR, IAPP POLB 4810/4885MEN1 279/4885KMT2A 4392/4885
US-11786599-B2 Releasable conjugates GUSB, ABCB11, UGT2B7 POLB 1863/4885MEN1 2694/4885KMT2A 4144/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.