Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13338860 | 0.93 | UGT2B7 (0.50) | HTTNPSR1L3MBTL1CYP2A6TDP1 | |
| SCHEMBL20048709 | 0.93 | UGT2B7 (0.50) | HTTNPSR1L3MBTL1CYP2A6TDP1 | |
| SCHEMBL13338861 | 0.90 | UGT2B7 (0.47) | L3MBTL1TDP1UGT2B7SLC6A2SLC6A4 | |
| SCHEMBL18134989 | 0.89 | CYP2A6 (0.58) | HTTNPSR1L3MBTL1CYP2A6TDP1 | |
| SCHEMBL12111309 | 0.89 | CYP2A6 (0.58) | HTTNPSR1L3MBTL1CYP2A6TDP1 | |
| SCHEMBL12744246 | 0.89 | CYP2A6 (0.58) | HTTNPSR1L3MBTL1CYP2A6TDP1 | |
| SCHEMBL10053532 | 0.89 | CYP2A6 (0.58) | HTTNPSR1L3MBTL1CYP2A6TDP1 | |
| SCHEMBL16344274 | 0.88 | UGT2B7 (0.46) | L3MBTL1CYP2A6UGT2B7CYP1A2TSHR | |
| SCHEMBL13339006 | 0.88 | UGT2B7 (0.46) | L3MBTL1CYP2A6UGT2B7CYP1A2TSHR | |
| SCHEMBL15002694 | 0.87 | UGT2B7 (0.44) | L3MBTL1TDP1UGT2B7SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190280223-A1 | DIBENZO[D,B]SILOLE-BASED REACTIVE MESOGENS | LOMOX LIMITED (GB) | 2019-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190280223-A1 | DIBENZO[D,B]SILOLE-BASED REACTIVE MESOGENS | CCNB1, CCNE2, UBE2G2 | HTT 4101/4885NPSR1 2641/4885L3MBTL1 375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.