Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT2B7 | P16662 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13338860 | 1.00 | UGT2B7 (0.50) | UGT2B7MEN1KMT2ACYP1A2AOC3 | |
| SCHEMBL13338861 | 0.96 | UGT2B7 (0.47) | UGT2B7MEN1KMT2ACYP1A2AOC3 | |
| SCHEMBL16344274 | 0.95 | UGT2B7 (0.46) | UGT2B7MEN1KMT2ACYP1A2AOC3 | |
| SCHEMBL13339006 | 0.95 | UGT2B7 (0.46) | UGT2B7MEN1KMT2ACYP1A2AOC3 | |
| SCHEMBL21348038 | 0.93 | HTT (0.48) | UGT2B7MEN1KMT2ACYP1A2AOC3 | |
| SCHEMBL15002694 | 0.93 | UGT2B7 (0.44) | UGT2B7MEN1KMT2ACYP1A2AOC3 | |
| SCHEMBL13338904 | 0.92 | UGT2B7 (0.55) | UGT2B7MEN1KMT2ACYP1A2AOC3 | |
| SCHEMBL13339016 | 0.92 | UGT2B7 (0.43) | UGT2B7CYP1A2CYP2D6TDP1L3MBTL1 | |
| SCHEMBL13338910 | 0.91 | UGT2B7 (0.50) | UGT2B7MEN1KMT2ACYP1A2AOC3 | |
| SCHEMBL12292308 | 0.90 | RELA (0.47) | UGT2B7MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11316118-B2 | Dibenzo[d,B]silole-based reactive mesogens | LOMOX LIMITED (GB) | 2022-04-26 | — | — | US | disclosed |
| EP-3523313-B1 | DIBENZO[D,B]SILOLE-BASED REACTIVE MESOGENS | LOMOX LTD (GB) | 2021-05-05 | — | — | EP | disclosed |
| US-20190280223-A1 | DIBENZO[D,B]SILOLE-BASED REACTIVE MESOGENS | LOMOX LIMITED (GB) | 2019-09-12 | — | — | US | disclosed |
| WO-2018065786-A1 | DIBENZO[D,B]SILOLE-BASED REACTIVE MESOGENS | LOMOX LIMITED (GB) | 2018-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190280223-A1 | DIBENZO[D,B]SILOLE-BASED REACTIVE MESOGENS | CCNB1, CCNE2, UBE2G2 | UGT2B7 516/4885MEN1 780/4885KMT2A 867/4885 |
| US-11316118-B2 | Dibenzo[d,B]silole-based reactive mesogens | CCNB1, CCNE2, UBE2G2 | UGT2B7 516/4885MEN1 780/4885KMT2A 867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.