SCHEMBL21350486

SCHEMBL21350486

CC(C)c1cc(F)cc(OCC2CC2)c1

nearest known ligand 0.54

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KAT6A Q92794 2/20 0.39
FFAR1 O14842 2/20 0.38
FFAR4 Q5NUL3 1/20 0.37
ACACB O00763 1/20 0.36
ACACA Q13085 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL20190654 0.86 FFAR1 (0.38) KAT6AFFAR1
Hydrochloric Acid SCHEMBL20190655 0.86 FFAR1 (0.38) KAT6AFFAR1
SCHEMBL18374081 0.85 KAT6A (0.39) KAT6AFFAR1ACACBACACA
SCHEMBL20376634 0.85 KAT6A (0.39) KAT6AFFAR1ACACBACACA
SCHEMBL12077349 0.82 KAT6A (0.46) KAT6A
SCHEMBL20201680 0.81 KDM1A (0.40) ACACBACACA
SCHEMBL21610851 0.80 FFAR1 (0.41) FFAR1FFAR4ACACB
SCHEMBL20351738 0.79 KAT6A (0.42) KAT6AACACBACACA
SCHEMBL24180197 0.78 KAT6A (0.38) KAT6AFFAR4ACACB
SCHEMBL18374006 0.78 KAT6A (0.44) KAT6A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10829457-B2 Nitrogen ring linked deoxyuridine triphosphatase inhibitors CV6 THERAPEUTICS (NI) LIMITED (GB) 2020-11-10 US disclosed
US-10570098-B2 Hydantoin containing deoxyuridine triphosphatase inhibitors CV6 THERAPEUTICS (NI) LIMITED (GB) 2020-02-25 US disclosed
US-20190276410-A1 NITROGEN RING LINKED DEOXYURIDINE TRIPHOSPHATASE INHIBITORS CV6 THERAPEUTICS (NI) LIMITED (GB) 2019-09-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10829457-B2 Nitrogen ring linked deoxyuridine triphosphatase inhibitors DUT, DPYD, TYMP KAT6A 2222/4885FFAR1 4454/4885FFAR4 4661/4885
US-10570098-B2 Hydantoin containing deoxyuridine triphosphatase inhibitors DUT, TYMP, DPYD KAT6A 1511/4885FFAR1 4576/4885FFAR4 4718/4885
US-20190276410-A1 NITROGEN RING LINKED DEOXYURIDINE TRIPHOSPHATASE INHIBITORS DUT, DPYD, TYMP KAT6A 2222/4885FFAR1 4454/4885FFAR4 4661/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.