Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 20/20 | 0.70 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.49 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.49 |
| ▸ | SLC2A9 | Q9NRM0 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28417540 | 0.91 | SLC22A12 (0.70) | SLC22A12SLC22A6SLC22A11SLC2A9ABCG2 | |
| SCHEMBL21350521 | 0.87 | SLC22A12 (0.62) | SLC22A12SLC22A6SLC22A11SLC2A9ABCG2 | |
| SCHEMBL21350744 | 0.85 | SLC22A12 (0.51) | SLC22A12 | |
| SCHEMBL21331815 | 0.84 | SLC22A12 (0.53) | SLC22A12 | |
| SCHEMBL28415846 | 0.84 | SLC22A12 (0.50) | SLC22A12 | |
| SCHEMBL21350742 | 0.84 | SLC22A12 (0.50) | SLC22A12 | |
| SCHEMBL21350524 | 0.83 | SLC22A12 (1.00) | SLC22A12SLC22A6SLC22A11ABCG2 | |
| SCHEMBL21350620 | 0.83 | SLC22A12 (0.68) | SLC22A12SLC22A6SLC22A11ABCG2 | |
| SCHEMBL12070811 | 0.82 | SLC22A12 (1.00) | SLC22A12SLC22A6SLC22A11ABCG2 | |
| SCHEMBL21331861 | 0.81 | SLC22A12 (0.60) | SLC22A12SLC22A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440397-B | 3- (naphthalene-1-methyl substituted) pyridine derivative and synthesis method and application thereof | 南方医科大学 | 2020-06-05 | — | — | CN | disclosed |
| WO-2019169890-A1 | 3-(NAPHTHALENE-1-METHYL SUBSTITUTED)PYRIDINE DERIVATIVE, SYNTHETIC METHOD THEREFOR AND USE THEREOF | 南方医科大学 | 2019-09-12 | — | — | WO | disclosed |