Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.35 |
| ▸ | RELA | Q04206 | 2/20 | 0.35 |
| ▸ | MTOR | P42345 | 3/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21351372 | 0.97 | NPC1 (0.41) | NPC1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL21351136 | 0.94 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL21351425 | 0.90 | NPC1 (0.33) | NPC1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL21351280 | 0.89 | NPC1 (0.31) | NPC1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL21351376 | 0.88 | NPC1 (0.38) | NPC1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL21351394 | 0.88 | NPC1 (0.38) | NPC1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL21351396 | 0.87 | KDM4E (0.37) | KDM4EATML3MBTL1HPGD | |
| SCHEMBL21351375 | 0.86 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL21351374 | 0.85 | NPC1 (0.38) | NPC1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL21351405 | 0.85 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190280214-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION | 2019-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190280214-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | LEF1, OCIAD1, OCIAD2 | NPC1 1575/4885RAB9A 375/4885SMN1; SMN2 3926/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.