Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GALK1 | P51570 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21351106 | 0.86 | NPC1 (0.50) | SMN1; SMN2NPC1RAB9AMAPTLMNA | |
| SCHEMBL21351110 | 0.82 | NPC1 (0.46) | SMN1; SMN2NPC1RAB9AMAPTLMNA | |
| SCHEMBL21351338 | 0.80 | NPC1 (0.42) | SMN1; SMN2NPC1RAB9AMAPTLMNA | |
| SCHEMBL21351498 | 0.80 | SMN1; SMN2 (0.42) | SMN1; SMN2NPC1RAB9AMAPTLMNA | |
| SCHEMBL21351416 | 0.79 | NPC1 (0.53) | SMN1; SMN2NPC1RAB9AMAPTLMNA | |
| SCHEMBL21351100 | 0.78 | NPC1 (0.41) | SMN1; SMN2NPC1RAB9AMAPTLMNA | |
| SCHEMBL22057695 | 0.78 | NPC1 (0.45) | SMN1; SMN2NPC1RAB9AMAPTLMNA | |
| SCHEMBL21351405 | 0.78 | NPC1 (0.51) | SMN1; SMN2NPC1RAB9AMAPTLMNA | |
| SCHEMBL21351105 | 0.78 | SMN1; SMN2 (0.47) | SMN1; SMN2NPC1RAB9AMAPTLMNA | |
| SCHEMBL21351427 | 0.77 | NPC1 (0.54) | SMN1; SMN2NPC1RAB9AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190280214-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION | 2019-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190280214-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | LEF1, OCIAD1, OCIAD2 | SMN1; SMN2 3926/4885NPC1 1575/4885RAB9A 375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.