SCHEMBL21352437

SCHEMBL21352437

O=C(c1ccccc1)P(=O)(O)C(=O)c1ccccc1.[LiH]

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.55
CES1 P23141 3/20 0.48
CES2 O00748 2/20 0.48
TSHR P16473 2/20 0.48
DAO P14920 1/20 0.48
NAPRT Q6XQN6 1/20 0.48
TDP1 Q9NUW8 4/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
CA12 O43570 2/20 0.46
CA1 P00915 2/20 0.46
CA9 Q16790 2/20 0.46
HSD17B10 Q99714 2/20 0.46
ALOX15 P16050 2/20 0.46
ATM Q13315 1/20 0.46
HDAC3 O15379 1/20 0.46
IDO1 P14902 1/20 0.46
HDAC1 Q13547 1/20 0.46
HDAC7 Q8WUI4 1/20 0.46
HDAC2 Q92769 1/20 0.46
HDAC8 Q9BY41 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21352451 0.97 ALDH1A1 (0.57) ALDH1A1CES1CES2TSHRDAO
SCHEMBL21352452 0.95 ALDH1A1 (0.55) ALDH1A1CES1CES2TSHRDAO
SCHEMBL21352449 0.95 ALDH1A1 (0.55) ALDH1A1CES1CES2TSHRDAO
SCHEMBL21352443 0.95 ALDH1A1 (0.55) ALDH1A1CES1CES2TSHRDAO
Benzoylphosphonate SCHEMBL1508013 0.82 ALDH1A1 (0.57) ALDH1A1CES1CES2TSHRDAO
SCHEMBL21352431 0.80 HPGD (0.42) ALDH1A1CES1CES2TSHRDAO
Benzophenone SCHEMBL6938755 0.79 ALDH1A1 (0.78) ALDH1A1CES1CES2TSHRDAO
Benzophenone SCHEMBL15398321 0.79 ALDH1A1 (0.78) ALDH1A1CES1CES2TSHRDAO
SCHEMBL7565852 0.79 ALDH1A1 (0.60) ALDH1A1CES1CES2TSHRDAO
Benzophenone SCHEMBL15129074 0.79 ALDH1A1 (0.78) ALDH1A1CES1CES2TSHRDAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019175112-A1 NOVEL PHOTO-INITIATORS AND THEIR APPLICATION ETH ZURICH (CH) 2019-09-19 WO disclosed
EP-3539969-A1 NOVEL PHOTO-INITIATORS AND THEIR APPLICATION ETH Zurich (CH) 2019-09-18 EP disclosed