Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | LDHA | P00338 | 2/20 | 0.36 |
| ▸ | LDHB | P07195 | 2/20 | 0.36 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxazole SCHEMBL21357664 | 0.91 | MAPT (0.38) | MAPTMEN1PABPC1KMT2AGAA | |
| SCHEMBL21357650 | 0.78 | MAPT (0.49) | MAPTMEN1PABPC1KMT2AGAA | |
| SCHEMBL21357607 | 0.78 | MAPT (0.45) | MAPTMEN1PABPC1KMT2AGAA | |
| SCHEMBL21357661 | 0.74 | CYP2A6 (0.61) | MAPTMEN1PABPC1KMT2AGAA | |
| SCHEMBL21357665 | 0.71 | — | — | |
| SCHEMBL21357580 | 0.71 | MAPT (0.43) | MAPTMEN1PABPC1KMT2AGAA | |
| SCHEMBL21357596 | 0.62 | KMT2A (0.41) | MAPTMEN1PABPC1KMT2AGAA | |
| SCHEMBL17712558 | 0.62 | MAOB (0.62) | MAPTMEN1PABPC1KMT2AGAA | |
| SCHEMBL21357625 | 0.62 | MAPT (0.44) | MAPTKMT2AGAATP53POLB | |
| SCHEMBL3166374 | 0.61 | TAAR1 (0.59) | MAPTMEN1PABPC1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019175464-A1 | COMPOUNDS USEFUL AS INHIBITORS OF SODIUM-CALCIUM EXCHANGER (NCX) | ORION CORPORATION (FI) | 2019-09-19 | — | — | WO | disclosed |