Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21357650 | 0.74 | MAPT (0.49) | MAPTMEN1KMT2APABPC1GAA | |
| SCHEMBL21357481 | 0.71 | MAPT (0.41) | MAPTMEN1KMT2APABPC1ALDH3A1 | |
| SCHEMBL21357607 | 0.71 | MAPT (0.45) | MAPTMEN1KMT2APABPC1ALDH3A1 | |
| SCHEMBL21357661 | 0.70 | CYP2A6 (0.61) | MAPTMEN1KMT2APABPC1GAA | |
| SCHEMBL11513455 | 0.67 | MEN1 (0.66) | MAPTMEN1KMT2APABPC1ALDH3A1 | |
| SCHEMBL23224041 | 0.65 | MAPT (0.46) | MAPTMEN1KMT2APABPC1ALDH3A1 | |
| SCHEMBL28134076 | 0.65 | MAPT (0.46) | MAPTMEN1KMT2APABPC1GFER | |
| SCHEMBL29659123 | 0.65 | MAPT (0.46) | MAPTMEN1KMT2APABPC1ALDH3A1 | |
| SCHEMBL631579 | 0.65 | MAPT (0.46) | MAPTMEN1KMT2APABPC1ALDH3A1 | |
| SCHEMBL11935970 | 0.65 | MAPT (0.54) | MAPTMEN1KMT2APABPC1ALDH3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019175464-A1 | COMPOUNDS USEFUL AS INHIBITORS OF SODIUM-CALCIUM EXCHANGER (NCX) | ORION CORPORATION (FI) | 2019-09-19 | — | — | WO | disclosed |