Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 1/20 | 0.61 |
| ▸ | S1PR3 | Q99500 | 12/20 | 0.60 |
| ▸ | FBP1 | P09467 | 2/20 | 0.55 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17469473 | 0.82 | S1PR3 (0.60) | PIK3CGS1PR3FBP1PSMB8PSMB5 | |
| SCHEMBL18028787 | 0.82 | S1PR3 (0.60) | PIK3CGS1PR3FBP1PSMB8PSMB5 | |
| SCHEMBL23933083 | 0.79 | S1PR3 (0.54) | PIK3CGS1PR3FBP1PSMB8PSMB5 | |
| SCHEMBL2134640 | 0.79 | MAPT (0.54) | S1PR3FBP1MAPTRAB9AS1PR1 | |
| SCHEMBL17465715 | 0.78 | S1PR3 (0.56) | PIK3CGS1PR3FBP1PSMB8PSMB5 | |
| SCHEMBL2137199 | 0.78 | HDAC7 (0.45) | PIK3CGS1PR3FBP1MAPTRAB9A | |
| SCHEMBL17664125 | 0.76 | S1PR3 (1.00) | S1PR3S1PR1 | |
| SCHEMBL21154138 | 0.76 | S1PR3 (0.54) | PIK3CGS1PR3FBP1PSMB8PSMB5 | |
| SCHEMBL19899789 | 0.76 | S1PR3 (0.50) | PIK3CGS1PR3FBP1PSMB8PSMB5 | |
| SCHEMBL9896463 | 0.76 | PIK3CG (1.00) | PIK3CGS1PR3FBP1PSMB8PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8242278-B2 | Process for producing biaryl compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-14 | — | — | US | disclosed |
| US-20120101278-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | HAGIYA KOJI (JP) | 2012-04-26 | — | — | US | disclosed |
| EP-1473286-B1 | PROCESS FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2009-11-04 | — | — | EP | disclosed |
| US-20090216017-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | HAGIYA KOJI | 2009-08-27 | — | — | US | disclosed |
| US-7554000-B2 | Process for producing biaryl compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-06-30 | — | — | US | disclosed |
| CN-1303043-C | Process for producing biaryl compound | SUMITOMO CHEMICAL CO (JP) | 2007-03-07 | — | — | CN | disclosed |
| US-20050096471-A1 | Process for producing biaryl compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-05-05 | — | — | US | disclosed |
| EP-1473286-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2004-11-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101278-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | PPOX, CAT, TYR | PIK3CG 2501/4885S1PR3 3035/4885FBP1 1850/4885 |
| US-20090216017-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | PPOX, CAT, TYR | PIK3CG 2501/4885S1PR3 3035/4885FBP1 1850/4885 |
| US-20050096471-A1 | Process for producing biaryl compound | PPOX, CAT, TYR | PIK3CG 2501/4885S1PR3 3035/4885FBP1 1850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.