Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TKT | P29401 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12776166 | 0.75 | DGAT1 (0.42) | TKTDGAT1 | |
| SCHEMBL27928345 | 0.72 | TKT (0.40) | TKTDGAT1 | |
| SCHEMBL30338990 | 0.69 | TKT (0.41) | TKTDGAT1P2RX3P2RX2 | |
| SCHEMBL12877696 | 0.69 | — | — | |
| SCHEMBL11319147 | 0.69 | — | — | |
| SCHEMBL317516 | 0.67 | — | — | |
| SCHEMBL12844554 | 0.66 | TKT (0.44) | TKTDGAT1 | |
| SCHEMBL317515 | 0.65 | — | — | |
| SCHEMBL7118818 | 0.65 | — | — | |
| SCHEMBL12862586 | 0.65 | TKT (0.40) | TKTDGAT1P2RX3P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019177375-A1 | 2, 4, 5-SUBSTITUTED PYRIMIDINE DERIVATIVES, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER COMPRISING SAME AS ACTIVE INGREDIENT | 포로노이바이오 주식회사 | 2019-09-19 | — | — | WO | disclosed |