Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | CCR6 | P51684 | 1/20 | 0.52 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.32 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.32 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | WRN | Q14191 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butyramide SCHEMBL4435118 | 0.85 | GSK3A (0.46) | GSK3AGSK3BCCR6ALDH1A1CYP1A2 | |
| Propionic Acid SCHEMBL264767 | 0.83 | GSK3A (0.55) | GSK3AGSK3BCCR6ALDH1A1CYP1A2 | |
| Urea SCHEMBL8556796 | 0.82 | GSK3A (0.69) | GSK3AGSK3BCCR6ALDH1A1 | |
| SCHEMBL27872896 | 0.81 | KDM4E (0.49) | GSK3AGSK3BCCR6ALDH1A1CYP1A2 | |
| Iodoacetamide SCHEMBL18114610 | 0.81 | GSK3A (0.52) | GSK3AGSK3BCCR6ALDH1A1CYP1A2 | |
| Propionic Acid SCHEMBL28981241 | 0.81 | GSK3A (0.52) | GSK3AGSK3BCCR6ALDH1A1CYP1A2 | |
| Ethylamine SCHEMBL28676595 | 0.79 | GSK3A (0.65) | GSK3AGSK3BCCR6ALDH1A1BLM | |
| Carbamic Acid SCHEMBL6022388 | 0.79 | GSK3A (0.65) | GSK3AGSK3BCCR6CYP2C19BLM | |
| Propionic Acid SCHEMBL28981239 | 0.79 | GSK3A (0.50) | GSK3AGSK3BCCR6ALDH1A1CYP1A2 | |
| Propane SCHEMBL28392088 | 0.79 | GSK3A (0.73) | GSK3AGSK3BCCR6ALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116199747-A | Lidamycin prodrug, preparation method and application thereof in preparation of antitumor drugs | 中国医学科学院医药生物技术研究所 | 2023-06-02 | — | — | CN | disclosed |
| CN-110452242-A | Pyrrolobenzodiazepines Zhuo and its conjugate | MEDIMMUNE LTD | 2019-11-15 | — | — | CN | disclosed |
| WO-2019176875-A1 | HETEROBIFUNCTIONAL COMPOUND HAVING MONODISPERSED POLYETHYLENE GLYCOL IN MAIN CHAIN OR SIDE CHAIN | 日油株式会社 | 2019-09-19 | — | — | WO | disclosed |
| CN-105307685-B | Pyrrolobenzodiazepines Zhuo and its conjugate | 麦迪穆有限责任公司 | 2019-03-08 | — | — | CN | disclosed |
| CN-105102003-B | Tall and erect-anti-PSMA antibody conjugates of Pyrrolobenzodiazepines | ADC疗法责任有限公司 | 2019-03-05 | — | — | CN | disclosed |
| CN-105102004-B | Pyrrolobenzodiazepines Zhuo-anti-CD22 antibody conjugate | ADC疗法责任有限公司 | 2019-01-25 | — | — | CN | disclosed |
| CN-108064276-A | Modified virus-like particle of CMV | 塞坝有限责任公司 | 2018-05-22 | — | — | CN | disclosed |
| CN-107108691-A | Protein production methods | UCB生物制药私人有限公司 | 2017-08-29 | — | — | CN | disclosed |
| CN-105307685-A | Pyrrolobenzodiazepines and conjugates thereof | SPIROGEN SARL | 2016-02-03 | — | — | CN | disclosed |
| CN-105189507-A | Pyrrolobenzodiazepines and conjugates thereof | SPIROGEN LTD | 2015-12-23 | — | — | CN | disclosed |
| CN-105102004-A | Pyrrolobenzodiazepine-anti-cd22 antibody conjugates | ADC THERAPEUTICS S RL | 2015-11-25 | — | — | CN | disclosed |
| CN-105050661-A | Pyrrolobenzodiazepine-antibody conjugates | ADC THERAPEUTICS S RL | 2015-11-11 | — | — | CN | disclosed |
| CN-104955485-A | Pyrrolobenzodiazepine-anti-her2 antibody conjugates | ADC THERAPEUTICS S RL | 2015-09-30 | — | — | CN | disclosed |
| CN-104726458-A | Lipid-modified Double-stranded Rna Having Potent Rna Interference Effect | NAT INST OF ADVANCED IND SCIEN | 2015-06-24 | — | — | CN | disclosed |
| CN-104447980-A | Glucagon analogs exhibiting enhanced solubility and stability in physiological pH buffers | UNIV INDIANA RES & TECH CORP | 2015-03-25 | — | — | CN | disclosed |
| CN-102088989-B | Glucagon analogs with enhanced solubility and stability in physiological pH buffers | UNIV INDIANA RES & TECH CORP | 2014-11-26 | — | — | CN | disclosed |
| CN-102099058-B | Novel reagents and method for conjugating biological molecules | POLYTHERICS LTD. (GB) | 2014-10-22 | — | — | CN | disclosed |
| CN-102933236-B | Pyrrolobenzodiazepines and conjugates thereof | SPIROGEN LTD. (CH) | 2014-10-08 | — | — | CN | disclosed |
| CN-102933236-A | Pyrrolobenzodiazepines and conjugates thereof | SPIROGEN LTD | 2013-02-13 | — | — | CN | disclosed |
| CN-101443356-A | Neuromedin U receptor agonists and uses thereof | MERCK & CO INC (US) | 2009-05-27 | — | — | CN | disclosed |