Propionic Acid

Propionic Acid

SCHEMBL264767

CCC(=O)O.O=C1C=CC(=O)N1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3A P49840 1/20 0.55
GSK3B P49841 1/20 0.55
CCR6 P51684 1/20 0.55
FFAR3 O14843 2/20 0.50
ALDH1A1 P00352 3/20 0.33
CYP1A2 P05177 1/20 0.33
HPGD P15428 1/20 0.33
CYP2C19 P33261 1/20 0.33
BLM P54132 1/20 0.33
WRN Q14191 1/20 0.33
HIF1A Q16665 1/20 0.33
KMT2A Q03164 1/20 0.32
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32
HDAC3 O15379 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
RECQL P46063 1/20 0.32
MAPT P10636 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propionic Acid SCHEMBL28981241 0.98 GSK3A (0.52) GSK3AGSK3BCCR6FFAR3ALDH1A1
Tetraethylene Glycol SCHEMBL29007236 0.84 MEN1 (0.39) GSK3AGSK3BCCR6FFAR3ALDH1A1
Butyric Acid SCHEMBL714988 0.84 FFAR3 (0.56) GSK3AGSK3BCCR6FFAR3ALDH1A1
SCHEMBL22981743 0.83 GSK3A (0.52) GSK3AGSK3BCCR6ALDH1A1CYP1A2
Propionamide SCHEMBL21359983 0.83 GSK3A (0.52) GSK3AGSK3BCCR6ALDH1A1CYP1A2
Glycolic Acid SCHEMBL29471409 0.82 GSK3A (0.58) GSK3AGSK3BCCR6HTTCA12
Succinic Acid SCHEMBL4127642 0.82 GSK3A (0.58) GSK3AGSK3BCCR6ALDH1A1CYP2C19
Acetic Acid SCHEMBL29870582 0.81 GSK3A (0.65) GSK3AGSK3BCCR6FFAR3
Acetic Acid SCHEMBL208214 0.81 GSK3A (0.65) GSK3AGSK3BCCR6FFAR3
Propionic Acid SCHEMBL28981239 0.81 GSK3A (0.50) GSK3AGSK3BCCR6FFAR3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 267 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250135043-A1 DUAL-TARGETING COMPOUND FOR FIBROBLAST ACTIVATION PROTEIN (FAP) AND INTEGRIN avB3, PREPARATION METHOD THEREFOR AND USE THEREOF YANTAI LANNACHENG BIOTECHNOLOGY CO., LTD. (CN) 2025-05-01 US claimed
CN-119736236-A Hydrogel for 3D culture of stem cells/organoids and preparation method thereof 昆明理工大学 2025-04-01 CN claimed
CN-119529003-A Albumin-binding doxorubicin prodrug, self-assembled nanoparticle thereof and application thereof 沈阳药科大学 2025-02-28 CN claimed
CN-118290405-B Fluorescent probe for targeting SLC7A5 high-expression tumor and preparation method and application thereof 江苏省人民医院(南京医科大学第一附属医院) 2025-02-28 CN claimed
CN-118290405-A Fluorescent probe for targeting SLC7A5 high-expression tumor and preparation method and application thereof 江苏省人民医院(南京医科大学第一附属医院) 2024-07-05 CN claimed
CN-116392642-A Extracellular matrix/glycopeptide hydrogel for heart failure treatment and preparation method thereof 中国医学科学院生物医学工程研究所 2023-07-07 CN claimed
CN-115895176-A Rubber processing aid and preparation method thereof 常州市五洲环保科技有限公司 2023-04-04 CN claimed
CN-115300640-A Novel linkers and their use for specific coupling of drugs and biomolecules 杭州多禧生物科技有限公司 2022-11-08 CN claimed
CN-113698335-A Specific conjugation of cell binding molecules 杭州多禧生物科技有限公司 2021-11-26 CN claimed
CN-111214461-B Preparation and application of sugar-targeted modified siRNA (small interfering ribonucleic acid) nanoparticles 河南大学 2021-04-16 CN claimed
CN-103732238-A Therapeutic compounds for immunomodulation AURIGENE DISCOVERY TECH LTD 2014-04-16 CN claimed
CN-1956998-B Method for the purification of albumin conjugates CONJUCHEM INC 2012-12-12 CN claimed
CN-101918841-A Peptide-lipid constructs and their use in diagnostic and therapeutic applications CRISTINA-SIMONA WEINBERG 2010-12-15 CN claimed
CN-101696240-A Long lasting growth hormone releasing factor derivatives CONJUCHEM INC 2010-04-21 CN claimed
EP-2016942-A1 Methods and compositions for the prevention and treatment of atherosclerosis, restenosis and related disorders CELGENE CORPORATION (US) 2009-01-21 EP claimed
US-20080146783-A1 Method for the purification of albumin conjugates CONJUCHEM BIOTECHNOLOGIES INC. 2008-06-19 US claimed
CN-1956998-A Method for the purification of albumin conjugates CONJUCHEM INC (CA) 2007-05-02 CN claimed
EP-1242082-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF ATHEROSCLEROSIS, RESTENOSIS AND RELATED DISORDERS CELGENE CORPORATION (US) 2002-09-25 EP claimed
US-20020054899-A1 Methods and compositions for the prevention and treatment of atherosclerosis, restenosis and related disorders CELGENE CORP. 2002-05-09 US claimed
WO-2001043743-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF ATHEROSCLEROSIS, RESTENOSIS AND RELATED DISORDERS CELGENE CORP. (US) 2001-06-21 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250135043-A1 DUAL-TARGETING COMPOUND FOR FIBROBLAST ACTIVATION PROTEIN (FAP) AND INTEGRIN avB3, PREPARATION METHOD THEREFOR AND USE THEREOF FAP, ITGAV, ITGB3 GSK3A 1063/4885GSK3B 645/4885CCR6 2332/4885
US-20080146783-A1 Method for the purification of albumin conjugates ALB, DNPEP, SLC7A1 GSK3A 4403/4885GSK3B 4684/4885CCR6 1699/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.