Ethylene

Ethylene

SCHEMBL21360008

C=C.C=CCc1ccccc1OC

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.50
KMT2A Q03164 1/20 0.50
TAAR1 Q96RJ0 1/20 0.50
ALDH1A1 P00352 4/20 0.49
CHRM2 P08172 1/20 0.48
CHRM1 P11229 1/20 0.48
ALOX5 P09917 1/20 0.47
GABRA1 P14867 1/20 0.47
CNR2 P34972 1/20 0.47
GABRB2 P47870 1/20 0.47
ACHE P22303 1/20 0.47
GAA P10253 1/20 0.47
MAPT P10636 1/20 0.47
PPARG P37231 1/20 0.47
PPARD Q03181 1/20 0.47
PPARA Q07869 1/20 0.47
ADRB2 P07550 3/20 0.47
ADRB1 P08588 3/20 0.47
LMNA P02545 1/20 0.47
HTR1A P08908 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29890976 0.98 IDO1 (0.52) IDO1KMT2ATAAR1ALDH1A1CHRM2
SCHEMBL592331 0.98 IDO1 (0.52) IDO1KMT2ATAAR1ALDH1A1CHRM2
Bromide SCHEMBL28225208 0.96 IDO1 (0.50) IDO1KMT2ATAAR1ALDH1A1CHRM2
Bicarbonate SCHEMBL3212051 0.89 KDM4E (0.54) KMT2AALDH1A1KDM4E
Estragole SCHEMBL29106756 0.85 ALDH1A1 (0.69) KMT2AALDH1A1ALOX5GABRA1CNR2
Ethylene SCHEMBL173231 0.83 ALDH1A1 (0.49) ALDH1A1GABRA1GABRB2ADRB2ADRB1
SCHEMBL895338 0.81 KDM4E (0.48) KMT2AALDH1A1ADRB2ADRB1LMNA
SCHEMBL7831223 0.81 IDO1 (0.55) IDO1TAAR1ALDH1A1CHRM2CHRM1
SCHEMBL88415 0.81 ALDH1A1 (0.50) ALDH1A1GABRA1GABRB2ADRB2ADRB1
SCHEMBL3955458 0.81 ALDH1A1 (0.50) ALDH1A1GABRA1GABRB2ADRB2ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019177110-A1 MOLDED PRODUCT COMPRISING POLARIZED OLEFIN-BASED POLYMER AND PROPERTY THEREOF 国立研究開発法人理化学研究所 2019-09-19 WO disclosed