Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 20/20 | 1.00 |
| ▸ | KCNK9 | Q9NPC2 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29432816 | 1.00 | KCNK3 (1.00) | KCNK3KCNK9 | |
| SCHEMBL21360501 | 0.92 | KCNK3 (1.00) | KCNK3KCNK9 | |
| SCHEMBL29458039 | 0.92 | KCNK3 (1.00) | KCNK3KCNK9 | |
| SCHEMBL25426294 | 0.92 | KCNK3 (1.00) | KCNK3KCNK9 | |
| SCHEMBL21360480 | 0.90 | KCNK3 (1.00) | KCNK3KCNK9 | |
| SCHEMBL29458035 | 0.90 | KCNK3 (1.00) | KCNK3KCNK9 | |
| SCHEMBL18963200 | 0.89 | KCNK3 (1.00) | KCNK3KCNK9 | |
| SCHEMBL29458044 | 0.89 | KCNK3 (1.00) | KCNK3KCNK9 | |
| SCHEMBL22636272 | 0.88 | KCNK3 (0.79) | KCNK3KCNK9 | |
| SCHEMBL29458033 | 0.88 | KCNK3 (0.79) | KCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10414765-B2 | Substituted perhydropyrrolo[3,4-c]pyrrole derivatives and the use of same | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2019-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10414765-B2 | Substituted perhydropyrrolo[3,4-c]pyrrole derivatives and the use of same | PAH, EGLN3, HYOU1 | KCNK3 1716/4885KCNK9 2925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.