Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18985307 | 0.88 | GAA (0.56) | GAAKDM4EMAPTALDH1A1HTT | |
| SCHEMBL18985218 | 0.80 | KDM4E (0.45) | GAAKDM4EMAPTALDH1A1HTT | |
| SCHEMBL19017275 | 0.79 | GAA (0.51) | GAAKDM4EMAPTALDH1A1HTT | |
| SCHEMBL9970786 | 0.78 | GAA (0.61) | GAAKDM4EMAPTALDH1A1HTT | |
| SCHEMBL9970782 | 0.74 | MAPT (0.56) | GAAKDM4EMAPTALDH1A1HTT | |
| SCHEMBL21361321 | 0.74 | GAA (0.56) | GAAKDM4EMAPTALDH1A1HTT | |
| SCHEMBL21361326 | 0.72 | GAA (0.53) | GAAKDM4EMAPTALDH1A1HTT | |
| SCHEMBL9937465 | 0.71 | MAPT (0.49) | GAAKDM4EMAPTALDH1A1HTT | |
| 2-Mercaptonicotinic Acid SCHEMBL1289908 | 0.70 | GAA (1.00) | GAAKDM4EMAPTALDH1A1HTT | |
| SCHEMBL9936056 | 0.70 | GAA (0.54) | GAAKDM4EMAPTALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3390363-B1 | PROCESS FOR DEPIGMENTING KERATIN MATERIALS USING THIOPYRIDINONE COMPOUNDS | OREAL (FR) | 2019-09-18 | — | — | EP | disclosed |