Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9936824 | 0.81 | GAA (0.68) | GAAKDM4EMAPTNAPRTALDH1A1 | |
| SCHEMBL10704470 | 0.80 | GAA (0.67) | GAAKDM4EMAPTNAPRTALDH1A1 | |
| SCHEMBL13485775 | 0.78 | GAA (0.63) | GAAKDM4EMAPTNAPRTALDH1A1 | |
| SCHEMBL9970786 | 0.76 | GAA (0.61) | GAAKDM4EMAPTNAPRTALDH1A1 | |
| SCHEMBL9936595 | 0.76 | GAA (0.61) | GAAKDM4EMAPTNAPRTALDH1A1 | |
| SCHEMBL9936655 | 0.76 | KDM4E (0.61) | GAAKDM4EMAPTALDH1A1HTT | |
| SCHEMBL440492 | 0.76 | NAPRT (1.00) | GAAKDM4EMAPTNAPRTALDH1A1 | |
| SCHEMBL18985201 | 0.75 | GAA (0.59) | GAAKDM4EMAPTNAPRTALDH1A1 | |
| Hydrochloric Acid SCHEMBL14741024 | 0.74 | NAPRT (0.96) | GAAKDM4EMAPTNAPRTALDH1A1 | |
| Hydrochloric Acid SCHEMBL17597625 | 0.74 | NAPRT (0.96) | GAAKDM4EMAPTNAPRTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120153320-A | Colored curable resin composition, color filter, display device, and solid-state imaging element | 住友化学株式会社 | 2025-06-13 | — | — | CN | disclosed |
| US-20250090554-A1 | A METHOD OF TREATING DEPRESSION BY IMMUNE MODULATION | MYND LIFE SCIENCES INC (CA) | 2025-03-20 | — | — | US | disclosed |
| US-12012466-B2 | Peptide macrocycles against Acinetobacter baumannii | HOFFMANN-LA ROCHE INC. (US) | 2024-06-18 | — | — | US | disclosed |
| CN-110366556-B | Antibacterial peptide macrocyclic compounds and uses thereof | 豪夫迈·罗氏有限公司 | 2024-01-05 | — | — | CN | disclosed |
| US-20220411468-A1 | PEPTIDE MACROCYCLES AGAINST ACINETOBACTER BAUMANNII | HOFFMANN-LA ROCHE INC. (US) | 2022-12-29 | — | — | US | disclosed |
| EP-3609904-B1 | ANTI-BACTERIAL PEPTIDE MACROCYCLES AND USE THEREOF | HOFFMANN LA ROCHE (CH) | 2022-11-30 | — | — | EP | disclosed |
| US-11066443-B2 | Anti-bacterial peptide macrocycles and use thereof | HOFFMANN-LA ROCHE INC. (US) | 2021-07-20 | — | — | US | disclosed |
| EP-3368544-B1 | PEPTIDE MACROCYCLES AGAINST ACINETOBACTER BAUMANNII | HOFFMANN LA ROCHE (CH) | 2020-06-17 | — | — | EP | disclosed |
| EP-3609904-A1 | ANTI-BACTERIAL PEPTIDE MACROCYCLES AND USE THEREOF | H. Hoffnabb-La Roche Ag (CH) | 2020-02-19 | — | — | EP | disclosed |
| US-20200040031-A1 | ANTI-BACTERIAL PEPTIDE MACROCYCLES AND USE THEREOF | HOFFMANN LA ROCHE (US) | 2020-02-06 | — | — | US | disclosed |
| WO-2017072062-A1 | PEPTIDE MACROCYCLES AGAINST ACINETOBACTER BAUMANNII | F. HOFFMANN-LA ROCHE AG (CH) | 2017-05-04 | — | — | WO | disclosed |
| US-8450243-B2 | Herbicidal quinoline and 1,8-naphthyridine compounds | SYNGENTA LIMITED (GB) | 2013-05-28 | — | — | US | disclosed |
| EP-2417132-B1 | HERBICIDAL QUINOLINE AND 1,8-NAPHTHYRIDINE COMPOUNDS | SYNGENTA LTD (GB) | 2013-04-17 | — | — | EP | disclosed |
| US-20120094833-A1 | HERBICIDAL QUINOLINE AND 1,8 -NAPHTHYRIDINE COMPOUNDS | SYNGENTA CROP PROTECTION, LLC (US) | 2012-04-19 | — | — | US | disclosed |
| WO-2012045721-A2 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2012-04-12 | — | — | WO | disclosed |
| EP-1140873-B1 | IL-5 INHIBITING 6-AZAURACIL DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2007-06-27 | — | — | EP | disclosed |
| US-6803364-B1 | FOR TREATING EOSINOPHIL-DEPENDENT INFLAMMATORY DISEASES SUCH AS ASTHMA | JANSSEN PHARMACEUTICA N.V. (BE) | 2004-10-12 | — | — | US | disclosed |
| EP-1140873-A1 | IL-5 INHIBITING 6-AZAURACIL DERIVATIVES | Janssen Pharmaceutica N.V. (BE) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000037451-A1 | IL-5 INHIBITING 6-AZAURACIL DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2000-06-29 | — | — | WO | disclosed |
| US-5049545-A | ANTIDIABETIC | BEHRINGWERKE AKTIENGESELLSCHAFT (DE) | 1991-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11066443-B2 | Anti-bacterial peptide macrocycles and use thereof | CFTR, VIP, NGLY1 | GAA 1788/4885KDM4E 4687/4885MAPT 4718/4885 |
| US-20220411468-A1 | PEPTIDE MACROCYCLES AGAINST ACINETOBACTER BAUMANNII | VIP, ARG1, CX3CR1 | GAA 2654/4885KDM4E 4323/4885MAPT 4627/4885 |
| US-12012466-B2 | Peptide macrocycles against Acinetobacter baumannii | VIP, ARG1, CX3CR1 | GAA 2654/4885KDM4E 4323/4885MAPT 4627/4885 |
| US-20120094833-A1 | HERBICIDAL QUINOLINE AND 1,8 -NAPHTHYRIDINE COMPOUNDS | NQO2, QDPR, CYP4X1 | GAA 1091/4885KDM4E 2176/4885MAPT 4421/4885 |
| US-20200040031-A1 | ANTI-BACTERIAL PEPTIDE MACROCYCLES AND USE THEREOF | CFTR, VIP, NGLY1 | GAA 1788/4885KDM4E 4687/4885MAPT 4718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.