Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 5/20 | 0.53 |
| ▸ | DRD2 | P14416 | 4/20 | 0.53 |
| ▸ | DRD4 | P21917 | 4/20 | 0.53 |
| ▸ | DRD1 | P21728 | 2/20 | 0.53 |
| ▸ | DRD5 | P21918 | 2/20 | 0.53 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.44 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | PRCP | P42785 | 1/20 | 0.44 |
| ▸ | EBP | Q15125 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28225477 | 0.90 | CYP3A4 (0.43) | DRD3DRD2DRD4DRD1DRD5 | |
| SCHEMBL28848092 | 0.85 | CYP1A2 (0.55) | — | |
| SCHEMBL24067279 | 0.79 | ALDH1A1 (0.39) | SIGMAR1CARM1PRMT6 | |
| SCHEMBL21903015 | 0.79 | KMT2A (0.36) | SIGMAR1CARM1PRMT6 | |
| SCHEMBL31294280 | 0.76 | ALDH1A1 (0.46) | — | |
| SCHEMBL28524004 | 0.75 | ALDH1A1 (0.43) | — | |
| SCHEMBL3411535 | 0.75 | KMT2A (0.47) | — | |
| SCHEMBL28740025 | 0.75 | DPP7 (0.42) | — | |
| SCHEMBL1251145 | 0.75 | DPP7 (0.42) | — | |
| SCHEMBL4480785 | 0.74 | EPHX2 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857401-B1 | NOVEL -LACTAMASE INHIBITOR AND METHOD FOR PRODUCING SAME | MEIJI SEIKA PHARMA CO LTD (JP) | 2019-09-18 | — | — | EP | disclosed |