Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 12/20 | 0.37 |
| ▸ | BPTF | Q12830 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.31 |
| ▸ | IL1B | P01584 | 2/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20902637 | 0.92 | KAT2B (0.39) | KAT2BBPTFKDM4EALDH1A1 | |
| SCHEMBL3939409 | 0.80 | ADH1B (0.52) | KAT2BBPTF | |
| SCHEMBL11896733 | 0.78 | — | — | |
| SCHEMBL1934606 | 0.77 | — | — | |
| SCHEMBL13797755 | 0.74 | POLB (0.37) | KAT2B | |
| SCHEMBL1914090 | 0.74 | — | — | |
| SCHEMBL1914093 | 0.74 | — | — | |
| SCHEMBL7219700 | 0.74 | — | — | |
| SCHEMBL19826021 | 0.73 | BTK (0.42) | KDM4EALDH1A1 | |
| SCHEMBL16791394 | 0.73 | BTK (0.42) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857401-B1 | NOVEL -LACTAMASE INHIBITOR AND METHOD FOR PRODUCING SAME | MEIJI SEIKA PHARMA CO LTD (JP) | 2019-09-18 | — | — | EP | disclosed |