Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20936684 | 0.89 | ALDH1A1 (0.40) | GLAALDH1A1GAATSHRNPC1 | |
| SCHEMBL10139491 | 0.82 | ALDH1A1 (0.37) | ALDH1A1GAATSHRNPC1RAB9A | |
| SCHEMBL16657424 | 0.81 | TSHR (0.40) | ALDH1A1GAATSHRNPC1RAB9A | |
| SCHEMBL28136316 | 0.81 | TSHR (0.40) | ALDH1A1GAATSHRNPC1RAB9A | |
| SCHEMBL28135553 | 0.81 | TSHR (0.40) | ALDH1A1GAATSHRNPC1RAB9A | |
| SCHEMBL16611860 | 0.81 | TSHR (0.40) | ALDH1A1GAATSHRNPC1RAB9A | |
| SCHEMBL14315910 | 0.81 | TSHR (0.40) | ALDH1A1GAATSHRNPC1RAB9A | |
| SCHEMBL14299321 | 0.81 | TSHR (0.40) | ALDH1A1GAATSHRNPC1RAB9A | |
| SCHEMBL28136314 | 0.81 | TSHR (0.40) | ALDH1A1GAATSHRNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL18065042 | 0.80 | TSHR (0.42) | ALDH1A1GAATSHRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857401-B1 | NOVEL -LACTAMASE INHIBITOR AND METHOD FOR PRODUCING SAME | MEIJI SEIKA PHARMA CO LTD (JP) | 2019-09-18 | — | — | EP | disclosed |