SCHEMBL21362364

SCHEMBL21362364

C=C[C@@H]1CC[C@@H](NOCc2ccccc2)CN1

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.38
ALDH1A1 P00352 1/20 0.34
GAA P10253 1/20 0.34
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21362361 0.86 ALDH1A1 (0.36) BCHEALDH1A1GAATSHR
SCHEMBL15865519 0.79 TSHR (0.36) ALDH1A1GAATSHR
SCHEMBL19872340 0.79 TSHR (0.36) ALDH1A1GAATSHR
SCHEMBL994655 0.78 TSHR (0.38) BCHEALDH1A1GAATSHR
SCHEMBL994656 0.78 TSHR (0.38) BCHEALDH1A1GAATSHR
SCHEMBL17060192 0.78 HTR2C (0.41) BCHEALDH1A1GAA
SCHEMBL994657 0.78 TSHR (0.38) BCHEALDH1A1GAATSHR
SCHEMBL10139491 0.77 ALDH1A1 (0.37) ALDH1A1GAATSHR
SCHEMBL21293006 0.76 ALDH1A1 (0.35) BCHEALDH1A1GAATSHR
SCHEMBL17232240 0.76 ALDH1A1 (0.35) BCHEALDH1A1GAATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2857401-B1 NOVEL -LACTAMASE INHIBITOR AND METHOD FOR PRODUCING SAME MEIJI SEIKA PHARMA CO LTD (JP) 2019-09-18 EP disclosed