Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20157834 | 0.78 | — | — | |
| SCHEMBL20157908 | 0.78 | — | — | |
| SCHEMBL22980995 | 0.69 | HDAC6 (0.33) | — | |
| SCHEMBL21362400 | 0.69 | — | — | |
| SCHEMBL20157836 | 0.69 | CRHR1 (0.30) | — | |
| SCHEMBL21362487 | 0.68 | — | — | |
| SCHEMBL20157391 | 0.67 | — | — | |
| SCHEMBL20157846 | 0.67 | — | — | |
| SCHEMBL21352133 | 0.66 | MAPT (0.32) | — | |
| SCHEMBL20158138 | 0.66 | MAPT (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3539960-A1 | NITROGENOUS MACROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | Luoxin Pharmaceutical (Shanghai) Co., Ltd. (CN) | 2019-09-18 | — | — | EP | disclosed |