SCHEMBL213626

SCHEMBL213626

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nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 2/20 0.53
GSTK1 Q9Y2Q3 1/20 0.53
ALDH1A1 P00352 3/20 0.52
MAPT P10636 2/20 0.52
LMNA P02545 1/20 0.52
PTGS2 P35354 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
SLC7A11 Q9UPY5 1/20 0.50
MMP2 P08253 1/20 0.47
MME P08473 5/20 0.46
ACE P12821 3/20 0.46
ECE1 P42892 2/20 0.46
HPGD P15428 1/20 0.46
MAPK1 P28482 1/20 0.46
HSD17B10 Q99714 1/20 0.46
MEN1 O00255 1/20 0.46
BLM P54132 1/20 0.46
NPEPPS P55786 1/20 0.46
KMT2A Q03164 1/20 0.46
CPA1 P15085 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL213625 1.00 PTGS1 (0.53) PTGS1GSTK1ALDH1A1MAPTLMNA
SCHEMBL27574429 1.00 PTGS1 (0.53) PTGS1GSTK1ALDH1A1MAPTLMNA
SCHEMBL11766266 1.00 PTGS1 (0.53) PTGS1GSTK1ALDH1A1MAPTLMNA
SCHEMBL27922239 0.98 PTGS1 (0.51) PTGS1GSTK1ALDH1A1MAPTLMNA
SCHEMBL27922237 0.98 PTGS1 (0.51) PTGS1GSTK1ALDH1A1MAPTLMNA
SCHEMBL3393046 0.94 ALDH1A1 (0.52) PTGS1GSTK1ALDH1A1MAPTLMNA
SCHEMBL3393040 0.94 ALDH1A1 (0.52) PTGS1GSTK1ALDH1A1MAPTLMNA
Cysteine SCHEMBL6014792 0.94 PTGS1 (0.61) PTGS1GSTK1ALDH1A1MAPTLMNA
Cysteine SCHEMBL6014796 0.94 PTGS1 (0.61) PTGS1GSTK1ALDH1A1MAPTLMNA
Glycine SCHEMBL28155782 0.94 PTGS1 (0.49) PTGS1GSTK1ALDH1A1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2272 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
CN-122081132-A Lactobacillus johnsonii DA0207 and application thereof in periplaneta americana fermentation 2026-05-26 CN claimed
WO-2026106950-A1 METHODS AND COMPOSITIONS FOR REDUCING MALODOR TAXA TECHNOLOGIES, INC. (US) 2026-05-21 WO claimed
EP-3431488-B1 METHOD FOR PRODUCING CRYSTAL OF REDUCED GLUTATHIONE KYOWA HAKKO BIO CO LTD (JP) 2026-05-06 EP claimed
US-12595229-B2 Method for producing derivative of organic substance and method for analyzing sample containing organic substance AJINOMOTO CO., INC. (JP) 2026-04-07 US claimed
US-12584924-B2 Compositions and methods for diagnosing and treating chronic kidney disease SOCIETE DES PRODUITS NESTLE S.A. (CH) 2026-03-24 US claimed
US-20250334558-A1 TOTAL HYDROGEN SULFIDE QUANTIFICATION CLEVELAND CLINIC FOUND (US) 2025-10-30 US claimed
US-20250336540-A1 METABOLITE PREDICTORS FOR LUNG CANCER JANSSEN PHARMACEUTICA NV (BE) 2025-10-30 US claimed
US-20250326814-A1 MODIFIED OXYNTOMODULIN AND METHODS OF USE THEREOF OPKO BIOLOGICS LTD. (IL) 2025-10-23 US claimed
US-20250269072-A1 PROCESSES FOR PREPARING RADIOLABELLED CONJUGATES CENTENARY INST OF CANCER MEDICINE AND CELL BIOLOGY (AU) 2025-08-28 US claimed
EP-0675712-A4 REDUCTION OF HAIR GROWTH EMPLOYING SULFHYDRYL REACTIVE COMPOUNDS. HANDELMAN JOSEPH H (US) 1996-11-06 EP claimed
EP-0713694-A1 Permanent wave hair composition Wella Aktiengesellschaft (DE) 1996-05-29 EP claimed
WO-1996006604-A2 METHODS FOR IDENTIFYING AND TREATING RESISTANT TUMORS ELI LILLY AND COMPANY (US) 1996-03-07 WO claimed
EP-0675712-A1 REDUCTION OF HAIR GROWTH EMPLOYING SULFHYDRYL REACTIVE COMPOUNDS HANDELMAN, Joseph H. (US) 1995-10-11 EP claimed
US-5411991-A Applying to human skin, beards, reaction with cysteine GILLETTE COMPANY, THE, A DELAWARE CORPORATION 1995-05-02 US claimed
EP-0604433-A4 COMPOSITION AND METHOD FOR DISEASE TREATMENT. LIFE SCIENCES TECH INC (US) 1994-10-12 EP claimed
WO-1994014428-A1 REDUCTION OF HAIR GROWTH EMPLOYING SULFHYDRYL REACTIVE COMPOUNDS HANDELMAN, JOSEPH, H. (US) 1994-07-07 WO claimed
EP-0604433-A1 COMPOSITION AND METHOD FOR DISEASE TREATMENT LIFE SCIENCES' TECHNOLOGIES, INC. (US) 1994-07-06 EP claimed
WO-1992021368-A1 COMPOSITION AND METHOD FOR DISEASE TREATMENT LIFE SCIENCES' TECHNOLOGIES, INC. (US) 1992-12-10 WO claimed
WO-1990003666-A1 STATE OF CHARGE OF REDOX CELL UNISEARCH LIMITED (AU) 1990-04-05 WO claimed