Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 7/20 | 0.38 |
| ▸ | BRD4 | O60885 | 11/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21564880 | 0.92 | BRD4 (0.32) | MAPK14BRD4GRM2 | |
| SCHEMBL21564931 | 0.92 | P2RX7 (0.34) | MAPK14BRD4GRM2 | |
| SCHEMBL21564927 | 0.88 | IDO1 (0.34) | BRD4GRM2 | |
| SCHEMBL21362077 | 0.88 | BRD4 (0.40) | MAPK14BRD4GRM2 | |
| SCHEMBL21564746 | 0.87 | IDO1 (0.37) | — | |
| SCHEMBL21564908 | 0.87 | IDO1 (0.39) | — | |
| SCHEMBL21564922 | 0.87 | POLB (0.37) | — | |
| SCHEMBL21564753 | 0.85 | POLB (0.38) | — | |
| SCHEMBL21564907 | 0.84 | P2RX7 (0.36) | BRD4GRM2 | |
| SCHEMBL20157909 | 0.81 | BRD4 (0.34) | MAPK14BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3539960-A1 | NITROGENOUS MACROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | Luoxin Pharmaceutical (Shanghai) Co., Ltd. (CN) | 2019-09-18 | — | — | EP | disclosed |