Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 11/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20157926 | 0.91 | BRD4 (0.37) | BRD4CREBBPPOLBMAPT | |
| SCHEMBL21354490 | 0.89 | BRD4 (0.34) | BRD4CREBBPPOLBMAPT | |
| SCHEMBL20157899 | 0.89 | CNR2 (0.36) | BRD4POLBMAPT | |
| SCHEMBL21362726 | 0.85 | BRD4 (0.31) | BRD4 | |
| SCHEMBL21362158 | 0.84 | BRD4 (0.34) | BRD4CREBBP | |
| SCHEMBL21352136 | 0.83 | BRD4 (0.38) | BRD4 | |
| SCHEMBL21362162 | 0.83 | BRD4 (0.34) | BRD4CREBBPPOLBMAPT | |
| SCHEMBL21564850 | 0.82 | BRD4 (0.37) | BRD4 | |
| SCHEMBL21362138 | 0.82 | BRD4 (0.38) | BRD4 | |
| SCHEMBL20157930 | 0.81 | BRD4 (0.37) | BRD4CREBBPPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3539960-A1 | NITROGENOUS MACROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | Luoxin Pharmaceutical (Shanghai) Co., Ltd. (CN) | 2019-09-18 | — | — | EP | disclosed |