Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 8/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.32 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.32 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21352099 | 0.85 | BRD4 (0.34) | BRD4MAPTCREBBPPOLB | |
| SCHEMBL21362110 | 0.85 | BRD4 (0.34) | BRD4CREBBP | |
| SCHEMBL20157926 | 0.85 | BRD4 (0.37) | BRD4MAPTCREBBPPOLB | |
| SCHEMBL21352115 | 0.85 | BRD4 (0.36) | BRD4MAPTCREBBPPOLB | |
| SCHEMBL21362728 | 0.81 | BRD4 (0.36) | BRD4MAPTCREBBPPOLB | |
| SCHEMBL21354490 | 0.81 | BRD4 (0.34) | BRD4MAPTCREBBPPOLB | |
| SCHEMBL21549998 | 0.80 | BRD4 (0.35) | BRD4MAP2K2MAP2K1 | |
| SCHEMBL21362158 | 0.79 | BRD4 (0.34) | BRD4CREBBP | |
| SCHEMBL21362162 | 0.78 | BRD4 (0.34) | BRD4MAPTCREBBPPOLB | |
| SCHEMBL21362088 | 0.78 | BRD4 (0.42) | BRD4MAPTMAP2K2MAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086605-A1 | NITROGENOUS MACROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | 山东罗欣药业集团股份有限公司 | 2018-05-17 | — | — | WO | disclosed |