Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SLC26A6 | Q9BXS9 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2136769 | 0.89 | CD38 (0.42) | SMN1; SMN2L3MBTL1ALDH1A1PLA2G1BATG4B | |
| SCHEMBL2135378 | 0.88 | ABL1 (0.44) | CYP1A2CYP2C9CYP2C19ALDH1A1HPGD | |
| SCHEMBL2136420 | 0.88 | KCNN3 (0.47) | SMN1; SMN2L3MBTL1ALDH1A1HPGDMAPT | |
| SCHEMBL2136868 | 0.87 | ABL1 (0.47) | ALDH1A1CYP3A4HSP90AA1HSP90B1CNR1 | |
| SCHEMBL2134833 | 0.86 | HSP90AA1 (0.43) | SMN1; SMN2L3MBTL1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2136168 | 0.85 | HTT (0.47) | SMN1; SMN2L3MBTL1CYP2C19ALDH1A1CYP3A4 | |
| SCHEMBL14700174 | 0.85 | SMN1; SMN2 (0.43) | SMN1; SMN2L3MBTL1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2135041 | 0.85 | F2 (0.45) | SMN1; SMN2L3MBTL1ALDH1A1HPGDMAPT | |
| SCHEMBL2137867 | 0.84 | SMN1; SMN2 (0.41) | SMN1; SMN2L3MBTL1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2134202 | 0.83 | ABL1 (0.44) | ALDH1A1HPGDCYP3A4GAAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2445884-B1 | 4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | SYNGENTA LTD (GB) | 2013-02-13 | — | — | EP | disclosed |
| EP-2445884-B1 | 4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | SYNGENTA LTD (GB) | 2013-02-13 | — | — | EP | disclosed |
| US-20120100990-A1 | 4 -AMINOPICOLINATES AND THEIR USE AS HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-04-26 | — | — | US | disclosed |
| US-20120100990-A1 | 4 -AMINOPICOLINATES AND THEIR USE AS HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-04-26 | — | — | US | disclosed |
| US-20120100990-A1 | 4 -AMINOPICOLINATES AND THEIR USE AS HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-04-26 | — | — | US | disclosed |
| WO-2010149956-A1 | 4 -AMINOPICOLINATES AND THEIR USE AS HERBICIDES | SYNGENTA LIMITED (GB) | 2010-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120100990-A1 | 4 -AMINOPICOLINATES AND THEIR USE AS HERBICIDES | DDT, DAO, NPM1 | SMN1; SMN2 3068/4885L3MBTL1 1101/4885CYP1A2 209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.