Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | GCK | P35557 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2137980 | 0.91 | AHR (0.36) | AHRGCK | |
| SCHEMBL2136499 | 0.86 | AHR (0.36) | AHRL3MBTL1CCR2GCK | |
| SCHEMBL2136310 | 0.82 | AHR (0.33) | AHRL3MBTL1CCR2GCK | |
| SCHEMBL2136512 | 0.82 | AHR (0.37) | AHRL3MBTL1CCR2GCK | |
| SCHEMBL2138016 | 0.82 | AHR (0.36) | AHRGCK | |
| SCHEMBL2136182 | 0.81 | L3MBTL1 (0.44) | AHRL3MBTL1CCR2 | |
| Hydrochloric Acid SCHEMBL2140025 | 0.80 | AHR (0.36) | AHRGCK | |
| SCHEMBL2138644 | 0.79 | AHR (0.42) | AHRCCR2GCK | |
| SCHEMBL2138680 | 0.79 | AHR (0.36) | AHRGCK | |
| SCHEMBL2139189 | 0.78 | AHR (0.42) | AHRCCR2GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2447265-A1 | NOVEL THIOPHENE CARBOXAMIDE DERIVATIVE AND MEDICINAL USE OF SAME | Sanwa Kagaku Kenkyusho Co., Ltd (JP) | 2012-05-02 | — | — | EP | disclosed |
| US-20120101137-A1 | NOVEL THIOPHENECARBOXAMIDE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101137-A1 | NOVEL THIOPHENECARBOXAMIDE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | GCK, GCKR, HK2 | AHR 3039/4885L3MBTL1 4632/4885CCR2 1550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.