Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.61 |
| ▸ | MAP1LC3A | Q9H492 | 2/20 | 0.61 |
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.58 |
| ▸ | POLQ | O75417 | 1/20 | 0.58 |
| ▸ | ALB | P02768 | 1/20 | 0.58 |
| ▸ | KDR | P35968 | 1/20 | 0.58 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21363043 | 0.91 | MAP1LC3B (0.71) | MAP1LC3BMAP1LC3AHSP90AB1HSP90AA1POLQ | |
| SCHEMBL25906573 | 0.88 | HSP90AB1 (0.70) | MAP1LC3BMAP1LC3AHSP90AB1HSP90AA1POLQ | |
| SCHEMBL22888743 | 0.87 | MAP1LC3B (0.58) | MAP1LC3BMAP1LC3AHSP90AB1HSP90AA1POLQ | |
| SCHEMBL21363023 | 0.87 | MAP1LC3B (0.72) | MAP1LC3BMAP1LC3AHSP90AB1HSP90AA1POLQ | |
| SCHEMBL21363079 | 0.86 | HSP90AB1 (0.70) | MAP1LC3BMAP1LC3AHSP90AB1HSP90AA1POLQ | |
| SCHEMBL21363024 | 0.85 | MAP1LC3B (0.69) | MAP1LC3BMAP1LC3AHSP90AB1HSP90AA1POLQ | |
| SCHEMBL21363102 | 0.85 | MAP1LC3B (0.58) | MAP1LC3BMAP1LC3AHSP90AB1HSP90AA1POLQ | |
| SCHEMBL22888421 | 0.84 | MAP1LC3B (0.60) | MAP1LC3BMAP1LC3AHSP90AB1HSP90AA1POLQ | |
| SCHEMBL21363000 | 0.84 | MAP1LC3B (0.57) | MAP1LC3BMAP1LC3AHSP90AB1HSP90AA1POLQ | |
| SCHEMBL21363251 | 0.83 | MAP1LC3B (0.61) | MAP1LC3BMAP1LC3AHSP90AB1HSP90AA1POLQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019178119-A1 | AMINOCOUMARIN COMPOUNDS AND METHODS OF THEIR USE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-09-19 | — | — | WO | disclosed |