⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25946269 | 1.00 | — | — | |
| SCHEMBL12716792 | 0.94 | L3MBTL3 (0.34) | — | |
| SCHEMBL12716798 | 0.94 | L3MBTL3 (0.34) | — | |
| SCHEMBL12715134 | 0.94 | L3MBTL3 (0.34) | — | |
| SCHEMBL12422035 | 0.92 | FYN (0.35) | — | |
| SCHEMBL12716816 | 0.92 | FYN (0.35) | — | |
| SCHEMBL12422034 | 0.92 | FYN (0.35) | — | |
| SCHEMBL12717988 | 0.86 | KDM4E (0.55) | — | |
| SCHEMBL12716866 | 0.86 | KDM4E (0.55) | — | |
| SCHEMBL12716857 | 0.86 | KDM4E (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10815226-B2 | Heteroaryl compounds as inhibitors of necrosis, composition and application thereof | ACCRO BIOSCIENCE INC. (KY) | 2020-10-27 | — | — | US | disclosed |
| US-20190284180-A1 | HETEROARYL COMPOUNDS AS INHIBITORS OF NECROSIS, COMPOSITION AND APPLICATION THEREOF | ACCRO BIOSCIENCE (HK) LIMITED (HK) | 2019-09-19 | — | — | US | disclosed |