⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7356437 | 0.62 | — | — | |
| SCHEMBL7265390 | 0.62 | — | — | |
| SCHEMBL7423144 | 0.62 | — | — | |
| SCHEMBL9017094 | 0.59 | — | — | |
| SCHEMBL7266255 | 0.57 | — | — | |
| SCHEMBL7273627 | 0.57 | — | — | |
| SCHEMBL9761067 | 0.57 | — | — | |
| SCHEMBL7266247 | 0.57 | — | — | |
| SCHEMBL7266811 | 0.57 | — | — | |
| SCHEMBL10050837 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10710994-B2 | Oxadiazole transient receptor potential channel inhibitors | GENENTECH, INC. (US) | 2020-07-14 | — | — | US | disclosed |
| US-20190284179-A1 | OXADIAZOLE TRANSIENT RECEPTOR POTENTIAL CHANNEL INHIBITORS | GENENTECH, INC. (US) | 2019-09-19 | — | — | US | disclosed |