Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17A | Q9UEE5 | 9/20 | 0.66 |
| ▸ | STK17B | O94768 | 4/20 | 0.66 |
| ▸ | DNM2 | P50570 | 2/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | CCNK | O75909 | 1/20 | 0.47 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.47 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.43 |
| ▸ | POLA1 | P09884 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22508313 | 0.87 | STK17A (0.73) | STK17ASTK17BHRH3CCNKCDK13 | |
| SCHEMBL22508341 | 0.82 | STK17A (0.76) | STK17ASTK17BHRH3CCNKCDK13 | |
| SCHEMBL20154728 | 0.79 | STK17A (1.00) | STK17ASTK17BHRH3CCNKCDK13 | |
| SCHEMBL20154753 | 0.79 | STK17A (1.00) | STK17ASTK17B | |
| SCHEMBL20154840 | 0.79 | STK17A (1.00) | STK17ASTK17B | |
| SCHEMBL22490561 | 0.79 | STK17A (0.76) | STK17ASTK17BHRH3CCNKCDK13 | |
| SCHEMBL19477222 | 0.79 | TLR8 (0.63) | STK17ADNM2HRH3CCNKCDK13 | |
| SCHEMBL19476564 | 0.79 | TLR8 (0.63) | STK17ADNM2HRH3CCNKCDK13 | |
| SCHEMBL22508340 | 0.79 | STK17A (0.75) | STK17ASTK17BHRH3CCNKCDK13 | |
| SCHEMBL20154746 | 0.78 | STK17A (1.00) | STK17ASTK17B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3539951-A1 | NOVEL PYRIMIDINE COMPOUND, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING CANCER AND INFLAMMATORY DISEASES | Korea Research Institute of Chemical Technology (KR) | 2019-09-18 | — | — | EP | disclosed |