SCHEMBL21365599

SCHEMBL21365599

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-n4c5ccccc5c5cc6c7ccccc7n(-c7ccc(-c8nc(-c9ccccc9)nc(-c9ccccc9)n8)cc7)c6cc54)cc3)n2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.52
ATM Q13315 2/20 0.52
KDM4E B2RXH2 2/20 0.52
KMT2A Q03164 7/20 0.40
MEN1 O00255 5/20 0.40
MAPT P10636 4/20 0.40
ALDH1A1 P00352 3/20 0.40
HPGD P15428 2/20 0.40
HDAC4 P56524 1/20 0.39
RXRA P19793 1/20 0.39
RAC2 P15153 1/20 0.38
RAC3 P60763 1/20 0.38
CDC42 P60953 1/20 0.38
RAC1 P63000 1/20 0.38
PTGER4 P35408 1/20 0.37
PTPN1 P18031 1/20 0.37
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
IL1R1 P14778 1/20 0.37
NTSR1 P30989 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22595913 0.98 L3MBTL1 (0.50) L3MBTL1ATMKDM4EKMT2AMEN1
SCHEMBL10018665 0.98 L3MBTL1 (0.55) L3MBTL1ATMKDM4EKMT2AMEN1
SCHEMBL18505376 0.97 L3MBTL1 (0.53) L3MBTL1ATMKDM4EKMT2AMEN1
SCHEMBL21365501 0.97 L3MBTL1 (0.53) L3MBTL1ATMKDM4EKMT2AMEN1
SCHEMBL21365493 0.97 L3MBTL1 (0.53) L3MBTL1ATMKDM4EKMT2AMEN1
SCHEMBL21365850 0.97 L3MBTL1 (0.53) L3MBTL1ATMKDM4EKMT2AMEN1
SCHEMBL26053230 0.96 L3MBTL1 (0.47) L3MBTL1ATMKDM4EKMT2AMEN1
SCHEMBL12691106 0.95 L3MBTL1 (0.53) L3MBTL1ATMKDM4EKMT2AMEN1
SCHEMBL16521265 0.94 L3MBTL1 (0.46) L3MBTL1ATMKDM4EKMT2AMEN1
SCHEMBL16521250 0.94 L3MBTL1 (0.46) L3MBTL1ATMKDM4EKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3767698-B1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MAT CO LTD (JP) 2023-10-25 EP disclosed
US-11374178-B2 Organic electroluminescent element NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2022-06-28 US disclosed
US-20210151683-A1 LIGHT-EMITTING ELEMENT, AND DISPLAY, ILLUMINATOR, AND SENSOR EACH INCLUDING SAME TORAY INDUSTRIES, INC. (JP) 2021-05-20 US disclosed
US-20210119144-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2021-04-22 US disclosed
EP-3767698-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL Chemical & Material Co., Ltd. (JP) 2021-01-20 EP disclosed
EP-3605634-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL Chemical & Material Co., Ltd. (JP) 2020-02-05 EP disclosed
WO-2019176605-A1 ORGANIC ELECTROLUMINESCENT ELEMENT 日鉄ケミカル&マテリアル株式会社 2019-09-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210151683-A1 LIGHT-EMITTING ELEMENT, AND DISPLAY, ILLUMINATOR, AND SENSOR EACH INCLUDING SAME CBR3, INTS9, CBR1 L3MBTL1 208/4885ATM 2844/4885KDM4E 1196/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.