Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.63 |
| ▸ | RRM1 | P23921 | 1/20 | 0.62 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.59 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.59 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.59 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.55 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.55 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.55 |
| ▸ | S1PR5 | Q9H228 | 4/20 | 0.55 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.47 |
| ▸ | TLR2 | O60603 | 6/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22922239 | 0.95 | DPP7 (0.69) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL23007634 | 0.95 | DPP7 (0.69) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| Bromide SCHEMBL20542993 | 0.93 | DPP7 (0.67) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| Bromide SCHEMBL20542996 | 0.93 | DPP7 (0.67) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL18807923 | 0.89 | DPP7 (0.61) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL13855557 | 0.89 | DPP7 (0.61) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL18807925 | 0.86 | TLR2 (0.61) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL23007762 | 0.86 | RRM1 (0.66) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL23007872 | 0.83 | DPP7 (0.58) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL11111978 | 0.82 | DPP7 (0.65) | DPP7RRM1GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019178166-A1 | AMPHIPHILIC THIOL COMPOUNDS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-09-19 | — | — | WO | disclosed |