⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22209898 | 0.71 | APOBEC3A (0.35) | — | |
| SCHEMBL21393396 | 0.62 | — | — | |
| SCHEMBL19464459 | 0.59 | — | — | |
| SCHEMBL19464456 | 0.59 | — | — | |
| SCHEMBL21393690 | 0.58 | APOBEC3A (0.35) | — | |
| SCHEMBL18783012 | 0.56 | — | — | |
| SCHEMBL21879818 | 0.54 | APOBEC3A (0.42) | — | |
| SCHEMBL10108327 | 0.51 | APOBEC3A (0.32) | — | |
| SCHEMBL21880074 | 0.49 | APOBEC3A (0.41) | — | |
| SCHEMBL3810295 | 0.49 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10913742-B2 | Oxadiazolones as transient receptor potential channel inhibitors | GENENTECH, INC. (US) | 2021-02-09 | — | — | US | disclosed |
| US-20190284189-A1 | OXADIAZOLONES AS TRANSIENT RECEPTOR POTENTIAL CHANNEL INHIBITORS | GENENTECH, INC. (US) | 2019-09-19 | — | — | US | disclosed |