Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 2/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21393693 | 0.77 | APOBEC3A (0.32) | APOBEC3AAPOBEC3G | |
| SCHEMBL21393576 | 0.72 | TDP1 (0.31) | TDP1 | |
| SCHEMBL19235764 | 0.67 | APOBEC3A (0.41) | APOBEC3AAPOBEC3GMAPTTDP1 | |
| SCHEMBL21879818 | 0.61 | APOBEC3A (0.42) | APOBEC3AAPOBEC3GKDM4ENPC1RAB9A | |
| SCHEMBL23718340 | 0.60 | APOBEC3A (0.41) | APOBEC3AAPOBEC3G | |
| SCHEMBL22209898 | 0.60 | APOBEC3A (0.35) | APOBEC3AAPOBEC3GNPC1RAB9A | |
| SCHEMBL15078306 | 0.58 | ALDH1A1 (0.45) | NPC1MAPTRAB9AKMT2A | |
| SCHEMBL21367563 | 0.58 | — | — | |
| SCHEMBL3054669 | 0.57 | APOBEC3A (0.42) | APOBEC3AAPOBEC3GKDM4ENPC1RAB9A | |
| SCHEMBL67836 | 0.57 | APOBEC3A (0.50) | APOBEC3AAPOBEC3GKDM4ENPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019182925-A1 | OXADIAZOLE TRANSIENT RECEPTOR POTENTIAL CHANNEL INHIBITORS | GENENTECH, INC. (US) | 2019-09-26 | — | — | WO | disclosed |